Novel biologics in inflammatory bowel disease

被引:16
|
作者
Papachristou, GI [1 ]
Plevy, S [1 ]
机构
[1] Univ Pittsburgh, Sch Med, Div Gastroenterol Hepatol & Nutr, Pittsburgh, PA 15261 USA
关键词
D O I
10.1016/j.gtc.2004.02.007
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Understanding of immunologic mechanisms involved in the initiation and perpetuation of chronic inflammation has led to new therapeutic opportunities in the inflammatory bowel diseases. The term "biologics" is used to distinguish new biotechnologic therapeutics from the conventional drugs used in the treatment of immune-mediated inflammatory disorders. This article reviews novel biologic therapies that are being investigated for the treatment of Crohn's disease and ulcerative colitis.
引用
收藏
页码:251 / +
页数:20
相关论文
共 50 条
  • [21] Optimization of the treatment with immunosuppressants and biologics in inflammatory bowel disease
    Sara Renna
    Ambrogio Orlando
    World Journal of Gastroenterology, 2014, (29) : 9675 - 9690
  • [22] Immunology of Inflammatory Bowel Disease and Molecular Targets for Biologics
    Dave, Maneesh
    Papadakis, Konstantinos A.
    Faubion, William A., Jr.
    GASTROENTEROLOGY CLINICS OF NORTH AMERICA, 2014, 43 (03) : 405 - +
  • [23] Optimization of the treatment with immunosuppressants and biologics in inflammatory bowel disease
    Renna, Sara
    Cottone, Mario
    Orlando, Ambrogio
    WORLD JOURNAL OF GASTROENTEROLOGY, 2014, 20 (29) : 9675 - 9690
  • [24] Advances in the development of new biologics in inflammatory bowel disease
    Ungar, Bella
    Kopylov, Uri
    ANNALS OF GASTROENTEROLOGY, 2016, 29 (03): : 243 - 248
  • [25] The role of biologics in the treatment of patients with inflammatory bowel disease
    Selinger, Christian P.
    Carbery, Isabel
    Al-Asiry, Jamal
    BRITISH JOURNAL OF HOSPITAL MEDICINE, 2018, 79 (12) : 686 - 693
  • [26] Oral Delivery of Biologics in Inflammatory Bowel Disease Treatment
    Zhang, Wunan
    Michalowski, Cecilia Bohns
    Beloqui, Ana
    FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, 2021, 9
  • [27] VACCINATION OF INFLAMMATORY BOWEL DISEASE PATIENTS ON IMMUNOMODULATORS AND BIOLOGICS
    Tan, J.
    Yap, K.
    Hong, L.
    Babu, P.
    GUT, 2015, 64 : A233 - A233
  • [28] Switching Between Biologics and Biosimilars in Inflammatory Bowel Disease
    Raffals, Laura E.
    Nguyen, Geoffrey C.
    Rubin, David T.
    CLINICAL GASTROENTEROLOGY AND HEPATOLOGY, 2019, 17 (05) : 818 - 823
  • [29] Inflammatory Bowel Disease: Updates on Molecular Targets for Biologics
    Katsanos, Konstantinos H.
    Papadakis, Konstantinos A.
    GUT AND LIVER, 2017, 11 (04) : 455 - 463
  • [30] Biologics Targeting in the Treatment of Inflammatory Bowel Disease: A Conundrum
    Rehman, Mahnoor
    Cancarevic, Ivan
    Iskander, Beshoy
    Lalani, Sanee
    Malik, Bilal Haider
    CUREUS JOURNAL OF MEDICAL SCIENCE, 2020, 12 (09)