Understanding of immunologic mechanisms involved in the initiation and perpetuation of chronic inflammation has led to new therapeutic opportunities in the inflammatory bowel diseases. The term "biologics" is used to distinguish new biotechnologic therapeutics from the conventional drugs used in the treatment of immune-mediated inflammatory disorders. This article reviews novel biologic therapies that are being investigated for the treatment of Crohn's disease and ulcerative colitis.
机构:Sheba Med Ctr, Dept Gastroenterol, Tel Hashomer, Israel
Ungar, Bella
Kopylov, Uri
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Sheba Med Ctr, Dept Gastroenterol, Tel Hashomer, Israel
Tel Aviv Univ, Sackler Fac Med, IL-52621 Ramat Gan, IsraelSheba Med Ctr, Dept Gastroenterol, Tel Hashomer, Israel
Kopylov, Uri
ANNALS OF GASTROENTEROLOGY,
2016,
29
(03):
: 243
-
248
机构:
Catholic Univ Louvain, Louvain Drug Res Inst, Adv Drug Delivery & Biomat, Brussels, BelgiumCatholic Univ Louvain, Louvain Drug Res Inst, Adv Drug Delivery & Biomat, Brussels, Belgium
Zhang, Wunan
Michalowski, Cecilia Bohns
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Catholic Univ Louvain, Louvain Drug Res Inst, Adv Drug Delivery & Biomat, Brussels, BelgiumCatholic Univ Louvain, Louvain Drug Res Inst, Adv Drug Delivery & Biomat, Brussels, Belgium
Michalowski, Cecilia Bohns
Beloqui, Ana
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Catholic Univ Louvain, Louvain Drug Res Inst, Adv Drug Delivery & Biomat, Brussels, BelgiumCatholic Univ Louvain, Louvain Drug Res Inst, Adv Drug Delivery & Biomat, Brussels, Belgium