Kasabach-Merritt Phenomenon Case Series and Retrospective Review of the Mayo Clinic Experience

被引:71
|
作者
Rodriguez, Vilmarie [1 ]
Lee, Adrianna [2 ]
Wittman, Patricia M. [3 ]
Anderson, Peter A. [4 ]
机构
[1] Mayo Clin, Div Pediat Hematol & Oncol, Rochester, MN 55905 USA
[2] Mayo Clin, Dept Pediat & Adolescent Med, Rochester, MN 55905 USA
[3] Mayo Clin, Dept Dermatol, Rochester, MN 55905 USA
[4] Univ Texas MD Anderson Canc Ctr, Dept Pediat, Houston, TX 77030 USA
关键词
Kasabach-Merritt phenomenon; thrombocytopenia; tufted angioma; INTERFERON-ALPHA-2B; HEMANGIOMAS; CHILDREN;
D O I
10.1097/MPH.0b013e3181a71830
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Kasabach-Merritt phenomenon (KMP) is a rare thrombocytopenic consumption coagulopathy associated with an enlarging tufted angioma or kaposiform hemangioendothelioma. We report a case series of patients with KMP and discuss the treatment options and outcomes. Nine patients with a diagnosis of KMP were identified through retrospective chart review-6 had "definite KMP" and 3 had "less likely KMP." The hematologic features of KMP and those of chronic coagulopathy seen with other vascular malformations can be similar, which makes KMP difficult to distinguish.
引用
收藏
页码:522 / 526
页数:5
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