Effects of antenatal magnesium sulfate treatment on cerebral blood flow velocities in preterm neonates

被引：13
|
作者：
Imamoglu, E. Y. [1 ]
Gursoy, T. [1 ]
Karatekin, G. [1 ]
Ovali, F. [1 ]
机构：
[1] Zeynep Kamil Matern & Childrens Training & Res Ho, Neonatal Intens Care Unit Istanbul, Istanbul, Turkey
来源：
JOURNAL OF PERINATOLOGY | 2014年 / 34卷 / 03期
关键词：
doppler; middle cerebral artery; magnesium; prematurity; VISCERAL ARTERIES; HEAD POSITION; DOPPLER; INFANTS; BRAIN; PRESSURE; HEMODYNAMICS; RELAXATION; HEMORRHAGE; PREGNANCY;
D O I：
10.1038/jp.2013.182
中图分类号：
R71 [妇产科学];
学科分类号：
100211 ;
摘要：
OBJECTIVE: The objective of this study is to investigate the effects of antenatal magnesium sulfate (MgSO4) on cerebral blood flow (CBF) velocities in preterm neonates. STUDY DESIGN: In this prospective case-control study, we included 53 neonates born between 26 and 34 weeks of gestation. Twenty neonates were exposed to MgSO4 antenatally and 33 were not. Serial daily Doppler flow measurements of middle cerebral artery (MCA) were performed. RESULT: Significantly increased MCA mean velocities were found in the MgSO4 group. A progressive increase in serial Doppler measurements of MCA mean velocity from day 1 to day 5 of life was detected in both groups. CONCLUSION: There is significant increase in MCA mean velocities in preterm neonates receiving antenatal MgSO4. This increment in CBF velocities might explain the protective role of MgSO4 in ischemic events and hypoxic brain damage.
引用
收藏
页码：192 / 196
页数：5
相关论文
共 50 条
  • [41] Magnesium sulfate and cerebral palsy in preterm infants
    Dammann, O
    Dammann, CEL
    Leviton, A
    GEBURTSHILFE UND FRAUENHEILKUNDE, 1997, 57 (12) : 670 - 674
  • [42] Antenatal Magnesium Sulfate Decreases Risk of Cerebral Palsy
    Al-Salam, Zakariya
    JOURNAL OF CLINICAL NEONATOLOGY, 2012, 1 (01) : 13 - +
  • [43] Antenatal Magnesium Sulfate Exposure and Ponderal Index in Preterm Infants
    Deihl, Tiffany E.
    Simhan, Hyagriv N.
    AMERICAN JOURNAL OF PERINATOLOGY, 2019, 36 (03) : 329 - 334
  • [44] Antenatal magnesium sulfate: neuro-protection for preterm infants
    Oddie, S.
    Tuffnell, D. J.
    McGuire, W.
    ARCHIVES OF DISEASE IN CHILDHOOD-FETAL AND NEONATAL EDITION, 2015, 100 (06): : F553 - F557
  • [45] Influence of maternal magnesium sulphate and ritodrine treatment on cerebral blood flow velocity of the preterm newborn
    Pezzati, M
    Giani, T
    Gambi, B
    Dani, C
    Bertini, G
    Biagiotti, R
    Rubaltelli, FF
    ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA, 2001, 80 (09) : 818 - 823
  • [46] THE INFLUENCE OF RESUSCITATION PROCEDURES ON CEREBRAL BLOOD-FLOW VELOCITIES IN PRETERM INFANTS
    IPSIROGLU, OS
    PESSENHOFER, H
    ROSEGGER, H
    PEDIATRIC RESEARCH, 1994, 35 (02) : 273 - 273
  • [47] Immediate clinical outcomes in preterm neonates receiving antenatal magnesium for neuroprotection
    Basu, Sudeepta Kumar
    Chickajajur, Vijay
    Lopez, Vivian
    Bhutada, Alok
    Pagala, Murali
    Rastogi, Shantanu
    JOURNAL OF PERINATAL MEDICINE, 2012, 40 (02) : 185 - 189
  • [48] Maternal magnesium sulfate treatment is associated with reduced brain-blood flow perfusion in preterm infants
    Rantonen, T
    Kääpä, P
    Grönlund, J
    Ekblad, U
    Helenius, H
    Kero, P
    Välimäki, I
    CRITICAL CARE MEDICINE, 2001, 29 (07) : 1460 - 1465
  • [49] Effects of red blood cell transfusion on cerebral hemodynamics of preterm neonates
    Amendola, Caterina
    De Carli, Agnese
    Boggini, Tiziana
    Contini, Davide
    Passera, Sofia
    Pesenti, Nicola
    Spinelli, Lorenzo
    Giovannella, Martina
    Durduran, Turgut
    Weigel, Udo M.
    Torricelli, Alessandro
    Greisen, Gorm
    Fumagalli, Monica
    NEUROPHOTONICS, 2024, 11 (04)
  • [50] Metabolomic characteristics of cord blood from neonates with hyperkalemia after antenatal exposure to ritodrine and magnesium sulfate
    Inoue, Masanori
    Sekiguchi, Kazuhito
    Tsushita, Haruka
    Inoue, Naomi
    Maeda, Tomoki
    Itoh, Hiroki
    Ihara, Kenji
    SCIENTIFIC REPORTS, 2025, 15 (01):
12345