Inhibition of methicillin resistant Staphylococcus aureus by a plasma needle

被引:10
|
作者
Miletic, Maja [1 ]
Vukovic, Dragana [2 ]
Zivanovic, Irena [2 ]
Dakic, Ivana [2 ]
Soldatovic, Ivan [3 ]
Maletic, Dejan [4 ]
Lazovic, Sasa [4 ]
Malovic, Gordana [4 ]
Petrovic, Zoran Lj [4 ]
Puac, Nevena [4 ]
机构
[1] Univ Belgrade, Fac Med Dent, Belgrade 11000, Serbia
[2] Univ Belgrade, Inst Microbiol & Immunol, Fac Med, Belgrade 11000, Serbia
[3] Univ Belgrade, Inst Med Stat & Informat, Fac Med, Belgrade 11000, Serbia
[4] Univ Belgrade, Inst Phys, Belgrade 11080, Serbia
来源
CENTRAL EUROPEAN JOURNAL OF PHYSICS | 2014年 / 12卷 / 03期
关键词
non-thermal atmospheric plasmas; plasma needle; antimicrobial; methicillin resistant Staphylococcus aureus; biofilm; ATMOSPHERIC-PRESSURE PLASMA; NITRIC-OXIDE; BACTERIAL BIOFILMS; NONTHERMAL PLASMA; ESCHERICHIA-COLI; STERILIZATION; INACTIVATION; MEDICINE; INFECTIONS; ENDOSPORES;
D O I
10.2478/s11534-014-0437-z
中图分类号
O4 [物理学];
学科分类号
0702 ;
摘要
In numerous recent papers plasma chemistry of non equilibrium plasma sources operating at atmospheric pressure has been linked to plasma medical effects including sterilization. In this paper we present a study of the effectiveness of an atmospheric pressure plasma source, known as plasma needle, in inhibition of the growth of biofilm produced by methicillin resistant Staphylococcus aureus (MRSA). Even at the lowest powers the biofilms formed by inoculi of MRSA of 10(4) and 10(5) CFU have been strongly affected by plasma and growth in biofilms was inhibited. The eradication of the already formed biofilm was not achieved and it is required to go to more effective sources.
引用
收藏
页码:160 / 167
页数:8
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