Novel Synthesis of (E)-3-Arylidene-2,3-dihydrobenzo[b][1,4]oxazepin-4(5H)-ones Using Baylis-Hillman Derivatives via Reductive Cyclization

被引：9

作者：

Bakthadoss, Manickam ^{[1
]}

Murugan, Gandhi ^{[1
]}

机构：

[1] Univ Madras, Dept Organ Chem, Madras 600025, Tamil Nadu, India

来源：

SYNTHETIC COMMUNICATIONS | 2009年 / 39卷 / 07期

关键词：

Baylis-Hillman reaction; benzoxazepinones; Fe; AcOH; 4-methyl; 2-nitrophenol; ADDUCTS; CONVENIENT; FRAMEWORKS;

D O I：

10.1080/00397910802519166

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A simple synthesis of novel (E)-3-arylidene-2,3-dihydrobenzo[b][1,4]oxazepin-4(5H)-ones from bromides of the Baylis--Hillman adducts using Fe/AcOH for the in situ reduction of nitro group, into an amino group, followed by the cyclization as a key step, has been described.

引用

页码：1290 / 1298

页数：9

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