Controlled release of farmazin from thermosensitive gels based on poly(N-vinylcaprolactam)

被引：6
|
作者：
Iskakov, RM [1 ]
Sedinkin, SV [1 ]
Mamytbekov, GK [1 ]
Batyrbekov, EO [1 ]
Bekturov, EA [1 ]
Zhubanov, BA [1 ]
机构：
[1] Bekturov Inst Chem Sci, Almaty, Kazakhstan
来源：
RUSSIAN JOURNAL OF APPLIED CHEMISTRY | 2004年 / 77卷 / 02期
关键词：
D O I：
10.1023/B:RJAC.0000030380.07016.fa
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
With the aim to prolong the effect of a wide-spectrum antimicrobial agent, Farmazin (tylosine tartrate), this drug was immobilized on a gel of N-vinylcaprolactam-sodium itaconate copolymer, which undergoes a phase transition on heating. The phase transition, accompanied by a change in volume, in aqueous solutions of the pure copolymer get and that with the immobilized drug was studied.
引用
收藏
页码：339 / 341
页数：3
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