Ticagrelor-Induced complete heart block: A rare entity

被引:0
|
作者
Anand, Wagle Varun [1 ]
Khadke, Isha [1 ]
Padmakumar, R. [2 ]
Rao, M. Sudhakar [2 ]
Chogtu, Bharti [1 ]
机构
[1] Manipal Acad Higher Educ, Kasturba Med Coll, Dept Med Pharmacol, Manipal, Karnataka, India
[2] Manipal Acad Higher Educ, Kasturba Med Coll, Dept Cardiol, Manipal, Karnataka, India
关键词
Heart block; purinergic P2Y receptor antagonist; ticagrelor;
D O I
10.4103/jpp.JPP_121_19
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Ticagrelor, a purinergic P2Y12 receptor blocker, is a potent platelet antagonist and an important component in the treatment for acute coronary syndromes identified to have a potential risk to cause bradyarrhythmias. Here, we report the case of a diabetic patient of unstable angina with left bundle branch block who was prescribed ticagrelor post angioplasty. Electrocardiogram (ECG) revealed a complete heart block after about 1 week. Ticagrelor was stopped and replaced by clopidogrel. The patient became asymptomatic and ECG showed baseline rhythm after 1 week of stoppage of ticagrelor.
引用
收藏
页码:75 / 77
页数:3
相关论文
共 50 条
  • [21] TICAGRELOR-INDUCED IMMUNE THROMBOCYTOPENIA & RESPONSE TO HIGH DOSE DEXAMETHASONE
    Yong, C. H.
    Manchanda, S.
    Varikara, K.
    INTERNAL MEDICINE JOURNAL, 2018, 48 : 21 - 21
  • [22] TICAGRELOR INDUCED PULMONARY HEMORRHAGE - A RARE ENTITY NECESSITATING PROMPT RECOGNITION
    Abdulelah, Ahmed
    Abdulelah, Zaid A.
    Al-Fakhouri, Zaid
    Al-Husni, Dua
    Al-Dqour, Mohammad
    Al-Mousa, Eyas N., II
    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2024, 83 (13) : 3292 - 3292
  • [23] Ticagrelor-Induced Torsades de Pointes following Myocardial Infarction
    Bu, Seong Hyeon
    Kim, Sung-Hwan
    CASE REPORTS IN CARDIOLOGY, 2022, 2022
  • [24] Ticagrelor-induced renal failure leading to statin-induced rhabdomyolysis
    van Vuren, A. J.
    de Jong, B.
    Bootsma, H. P. R.
    Van der Veen, M. J.
    Feith, G. W.
    NETHERLANDS JOURNAL OF MEDICINE, 2015, 73 (03): : 136 - 138
  • [25] TICAGRELOR-INDUCED BLEEDING IN MICE CAN BE REVERSED BY FVIA (NOVOSEVEN®) AND FH
    Nylander, Sven
    Pehrsson, Susanne
    Hansson, Kenny
    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2013, 61 (10) : E212 - E212
  • [26] Circadian variation of ticagrelor-induced platelet inhibition in healthy adulty
    Fournier, Stephane
    Guenat, Florine
    Fournier, Anne
    Alberio, Lorenzo
    Bonny, Olivier
    Calderara, Debora Bertaggia
    Bardy, Daniel
    Lauriers, Nathalie
    Harbaoui, Brahim
    Monney, Pierre
    Pascale, Patrizio
    Eeckhout, Eric
    Muller, Olivier
    EUROPEAN HEART JOURNAL-CARDIOVASCULAR PHARMACOTHERAPY, 2018, 4 (03) : 166 - 171
  • [27] Factors Determining Ticagrelor-Induced Dyspnea in Patients with Acute Coronary Syndrome
    Tamakauskas, Vytenis
    Zaliunas, Remigijus
    Lesauskaite, Vaiva
    Kupstyte-Kristapone, Nora
    Sakalyte, Gintare
    Jurgaityte, Julija
    Ciapiene, Ieva
    Tatarunas, Vacis
    APPLIED SCIENCES-BASEL, 2022, 12 (19):
  • [28] Effect of altitude on ticagrelor-induced dyspnea in patients with acute coronary syndrome
    Kocabay, Gonenc
    Kivrak, Tarik
    Karaca, Ozkan
    Karasu, Mehdi
    Kaya, Hakki
    Kanar, Batur
    Orscelik, Ozcan
    Kobat, Mehmet Ali
    Yilmaz, Mehmet Birhan
    JOURNAL OF INTERNATIONAL MEDICAL RESEARCH, 2023, 51 (04)
  • [29] Ticagrelor-induced thrombotic thrombocytopenic purpura A case report and review of the literature
    Wang, Xiaoya
    Zhang, Shufang
    Li, Leiqing
    Hua, Junjie
    Zhu, Lei
    Li, Libin
    Zhang, Gensheng
    MEDICINE, 2018, 97 (26)
  • [30] A Rare Case of Complete Heart Block in a Young Patient
    Hindi, Zakaria
    Hindi, Yousef
    Batarseh, Rami
    CASE REPORTS IN CARDIOLOGY, 2018, 2018