Interaction between fulvic acids of different origins and active oxygen radicals

被引：0

作者：

Wang, CX ^{[1
]}

Wang, ZJ ^{[1
]}

Peng, A ^{[1
]}

Hou, JW ^{[1
]}

Xin, WJ ^{[1
]}

机构：

[1] CHINESE ACAD SCI,INST BIOPHYS,BEIJING 100101,PEOPLES R CHINA

来源：

SCIENCE IN CHINA SERIES C-LIFE SCIENCES | 1996年 / 39卷 / 03期

关键词：

fulvic acids; active oxygen radicals; spin trapping; Kaschin-Beck disease;

D O I：

暂无

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Using the spin trapping technique, the interaction between fulvic acids (FAs) of different origins and the active oxygen radicals was studied. The active oxygen radicals under study included superoxide anion (O-2 .(-)) produced by xanthine oxidase (XOD) and stimulated polymorphonuclear leukocytes (PMN) of human being and hydroxyl radical (. OH) produced from Fenton's reaction. It has been found that the FAs from both Kaschin-Beck disease (KBD) region and non-KBD region can accelerate the production of . OH and scavenge O-2 .(-). FA from peat on scavenge both O-2 .(-) and . OH. The results show that the behavior of KBD and non-KBD FAs differs clearly from peat FA. It has been concluded that the superoxidation damage of KBD induced by FA is mainly due to hydroxyl radical reaction initiated in biological system.

引用

页码：267 / 275

页数：9

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