Genetic susceptibility to multiple sclerosis

被引：0
|
作者：
Fontaine, B
Clerget-Darpoux, F
机构：
[1] Grp Hosp Pitie Salpetriere, Federat Neurol, F-75651 Paris 13, France
[2] Grp Hosp Pitie Salpetriere, INSERM, CJF0711, F-75651 Paris 13, France
[3] INSERM, U535, F-94275 Le Kremlin Bicetre, France
来源：
PATHOLOGIE BIOLOGIE | 2000年 / 48卷 / 01期
关键词：
genetics; HLA; multiple sclerosis;
D O I：
暂无
中图分类号：
R36 [病理学];
学科分类号：
100104 ;
摘要：
Although the clinical manifestations and neuropathological signs of multiple sclerosis (MS) have been known for a century, the cause of this disease has not yet been determined. The epidemiological studies indicate that MS is of multifactorial etiology, including both environmental and inherited (genetic predisposition) factors. The role of the HLA system in genetic predisposition to MS has been known since the 1970s. As a result of the progress made in human genetics, it is now possible to study genetic predisposition to MS. (C) 2000 Editions scientifiques et medicales Elsevier SAS.
引用
收藏
页码：87 / 92
页数：6
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