Preparation of poly(ε-caprolactone) microspheres and fibers with controllable surface morphology

被引：33
|
作者：
Huang, Xuewu [1 ]
Gao, Jiefeng [1 ,2 ,3 ]
Li, Wan [2 ]
Xue, Huaiguo [1 ]
Li, Robert K. Y. [2 ]
Mai, Yiu-Wing [3 ]
机构：
[1] Yangzhou Univ, Coll Chem & Chem Engn, Yangzhou 225002, Jiangsu, Peoples R China
[2] City Univ Hong Kong, Dept Phys & Mat Sci, Tat Chee Ave, Kowloon, Hong Kong, Peoples R China
[3] Univ Sydney, CAMT, Sch Aerosp Mech & Mech Engn J07, Sydney, NSW 2006, Australia
来源：
MATERIALS & DESIGN | 2017年 / 117卷
关键词：
Electro-spraying; Electrospinning; Non-solvent; Phase separation; Pores; POROUS POLYCAPROLACTONE MICROSPHERES; POLYMER MICROSPHERES; ELECTROHYDRODYNAMIC ATOMIZATION; NANOFIBERS; SOLVENT; PARTICLES; SCAFFOLD; FILM;
D O I：
10.1016/j.matdes.2016.12.096
中图分类号：
T [工业技术];
学科分类号：
08 ;
摘要：
Poly(epsilon-caprolactone) (PCL) microspheres with different surface architectures were prepared by electro-spraying a solution containing polymer, host solvent and guest solvent. With increasing polymer concentration, PCL gradually turned from collapsed particles to regular uniform microspheres and finally to fibers. Non-solvent induced phase separation was responsible for formation of surface pores, and the pore density on the microsphere surface could be varied by selecting different guest solvent or by changing the amount of the non-solvent. The surface morphology of electrospun fibers could be tuned from smooth to rough and porous by varying the weight ratio between non-solvent and polymer that controlled the coalescence of the non-solvent nuclei. (C) 2017 Elsevier Ltd. All rights reserved.
引用
收藏
页码：298 / 304
页数：7
相关论文
共 50 条
  • [41] PREPARATION AND IN VITRO EVALUATION OF FELODIPINE-LOADED POLY(ε-CAPROLACTONE) MICROSPHERES: QUALITY BY DESIGN APPROACH
    Achim, Marcela
    Tefas, Lucia Ruxandra
    Iovanov, Rares
    Vonica-Gligor, Andreea Loredana
    Barbu-Tudoran, Lucian
    Tomuta, Ioan
    FARMACIA, 2019, 67 (04) : 670 - 683
  • [42] Preparation of Ultrafine Poly(ε-caprolactone) Fibers Containing Silver Nanoparticles via Electrospinning Method
    Jia, Yongtang
    Liu, Qingqing
    Zhu, Xiangying
    ADVANCED TEXTILE MATERIALS, PTS 1-3, 2011, 332-334 : 1235 - 1238
  • [43] Preparation and Characterization of Phosphate Glass Fibers and Fabrication of Poly(caprolactone) Matrix Resorbable Composites
    Khan, Ruhul A.
    Parsons, A. J.
    Jones, I. A.
    Walker, G. S.
    Rudd, C. D.
    JOURNAL OF REINFORCED PLASTICS AND COMPOSITES, 2010, 29 (12) : 1838 - 1850
  • [44] Preparation and surface modification of magnetic poly(methyl methacrylate) microspheres
    Yang, CL
    Guan, YP
    Xing, JM
    Liu, JG
    An, ZT
    Liu, HZ
    SCIENCE IN CHINA SERIES B-CHEMISTRY, 2004, 47 (04): : 349 - 354
  • [45] Preparation and surface modification of magnetic poly(methyl methacrylate) microspheres
    YANG Chengli
    Science in China(Series B) , 2004, (04) : 349 - 354
  • [46] Preparation and surface modification of magnetic poly(methyl methacrylate) microspheres
    Chengli Yang
    Yueping Guan
    Jianmin Xing
    Junguo Liu
    Zhentao An
    Huizhou Liu
    Science in China Series B: Chemistry, 2004, 47 : 349 - 354
  • [47] Disodium norcantharidate-loaded poly(ε-caprolactone) microspheres II.: Modification of morphology and release behavior
    Wang, Shaobing
    Guo, Shengrong
    INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2008, 353 (1-2) : 15 - 20
  • [48] Generation of Monodisperse Mesoporous Silica Microspheres with Controllable Size and Surface Morphology in a Microfluidic Device
    Lee, Inho
    Yoo, Yeonshick
    Cheng, Zhengdong
    Jeong, Hae-Kwon
    ADVANCED FUNCTIONAL MATERIALS, 2008, 18 (24) : 4014 - 4021
  • [49] Characteristics of felodipine-located poly(ε-caprolactone) microspheres
    Kim, BK
    Hwang, SJ
    Park, JB
    Park, HJ
    JOURNAL OF MICROENCAPSULATION, 2005, 22 (02) : 193 - 203
  • [50] TAXOL ENCAPSULATION IN POLY(EPSILON-CAPROLACTONE) MICROSPHERES
    DORDUNOO, SK
    JACKSON, JK
    ARSENAULT, LA
    OKTABA, AMC
    HUNTER, WL
    BURT, HM
    CANCER CHEMOTHERAPY AND PHARMACOLOGY, 1995, 36 (04) : 279 - 282
12345