The Good, the Bad, or the Pretty: IL-17 Builds Lymphoid Tissues in the Brain

被引:0
|
作者
Becher, Burkhard [1 ]
机构
[1] Univ Zurich, Inst Expt Immunol Inflammat Res, CH-8057 Zurich, Switzerland
关键词
PRECURSORS; CELLS;
D O I
10.1016/j.immuni.2015.11.021
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Lymph node development depends on well-orchestrated interactions between lymphoid tissue inducer cells and stromal cells. In this issue of Immunity, Pikor and colleagues (2015) find that signals from IL-17-producing T helper cells can alter the stromal microenvironment of the inflamed brain to generate a neo-lymphoid organ that drives further inflammation.
引用
收藏
页码:1033 / 1034
页数:2
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