New Cobalt and Zinc Complexes with Schiff Base Ligands: Synthesis, Structures, and Biochemical Properties

Two similar Schiff base ligands 2-[(2-isopropylaminoethylimino) methyl]-5-methoxyphenol (HLa) and 2-ethoxy-6-[(2-isopropylaminoethylimino) methyl] phenol (HLb) reacting with cobalt perchlorate and zinc iodide, respectively, in methanol gave the complexes [CoL2a]center dot ClO4 (1) and [Zn(HLb)(2)I-2(m-OH)]center dot I center dot MeOH (2). Both complexes were characterized by elemental analyses and IR spectroscopic method in the solid state. Single-crystal X-ray analysis was performed, which reveals that (1) is a mononuclear cobalt complex, and (2) is a dinuclear zinc complex. The Co atom in (1) is in an octahedral coordination. The Zn atoms in (2) are in tetrahedral coordination. Antibacterial activities of the Schiff base ligands and the complexes have been studied on the strains B. subtilis, E. coli, and S. aureus.