The lost art of localization: Franc Ingraham's legacy in pediatric neurosurgery

被引:2
|
作者
Cohen, Alan R. [1 ]
Vogel, Timothy W. [1 ]
Lidov, Hart G. W. [2 ]
机构
[1] Harvard Univ, Dept Neurosurg, Boston Childrens Hosp, Sch Med, Boston, MA 02115 USA
[2] Harvard Univ, Dept Pathol, Boston Childrens Hosp, Sch Med, Boston, MA 02115 USA
关键词
brain tumor; cerebellum; pediatric neurosurgery; Ingraham; Farber; astrocytoma; Boston Children's Hospital; oncology; SUBDURAL-HEMATOMA; INFANCY;
D O I
10.3171/2013.8.PEDS1377
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
The authors describe an 8-year-old girl who underwent emergency posterior fossa surgery for resection of a large cerebellar astrocytoma in November 1939. The surgery was carried out by Franc D. Ingraham at Boston Children's Hospital a decade after he established the first pediatric neurosurgical service in the world at the same institution. Four years later the tumor recurred and the patient underwent repeat resection followed by external-beam radiation therapy. The pathological diagnosis by Sidney Farber was fibrillary astrocytoma. The young girl is currently a healthy, functional 82-year-old woman. The authors believe that this 74-year follow-up represents one of the longest in history, if not the longest, of a patient undergoing resection of a brain tumor. A recent MRI study shows postoperative changes with no evidence of residual or recurrent tumor. The original block tissue specimen had been preserved. It was restained and examined, revealing the pathological diagnosis to be juvenile pilocytic astrocytoma.
引用
收藏
页码:642 / 654
页数:13
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