Reverse seroconversion of hepatitis B virus after hematopoietic stem cell transplantation

被引：40

作者：

Goyama, S ^{[1
]}

Kanda, Y ^{[1
]}

Nannya, Y ^{[1
]}

Kawazu, M ^{[1
]}

Takeshita, M ^{[1
]}

Niino, M ^{[1
]}

Komeno, Y ^{[1
]}

Nakamoto, T ^{[1
]}

Kurokawa, M ^{[1
]}

Tsujino, S ^{[1
]}

Ogawa, S ^{[1
]}

Aoki, K ^{[1
]}

Chiba, S ^{[1
]}

Motokura, T ^{[1
]}

Shiratori, Y ^{[1
]}

Hirai, H ^{[1
]}

机构：

[1] Univ Tokyo, Grad Sch Med, Dept Hematol & Oncol, Bunkyo Ku, Tokyo 1138655, Japan

来源：

LEUKEMIA & LYMPHOMA | 2002年 / 43卷 / 11期

关键词：

hepatitis B virus; reverse seroconversion; hematopoietic stem cell transplantation; immunosuppression;

D O I：

10.1080/1042819021000033042

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Hepatitis B virus (HBV) reactivation in patients previously positive for hepatitis B surface antibody (HBsAb), so-called reverse seroconversion, has been considered to be a rare complication after hematopoietic stem cell transplantation (HSCT). We experienced two patients who developed reverse seroconversion among nine who were HBsAb positive and Hepatitis B core antibody (HBcAb) positive before HSCT; one after autologous bone marrow transplantation (BMT) and another after allogeneic peripheral blood stem cell transplantation (PBSCT). We reviewed the literature and considered that reverse seroconversion of HBV after HSCT is not uncommon among HBsAb positive recipients. The use of corticosteroids, the lack of HBsAb in donor, and a decrease in serum HBsAb and HBcAb levels may predict reverse seroconversion after HSCT.

引用

页码：2159 / 2163

页数：5

共 50 条

[31] The effect of hepatitis B virus status of donor on the hepatitis B virus serology of recipient after allogeneic hematopoietic cell transplantation
Soydan, EA
Idilman, R
Arat, M
Karayalcin, S
Ustun, C
Ozcan, M
Arslan, O
Beksac, M
Ilhan, O
Akan, H
BONE MARROW TRANSPLANTATION, 2003, 31 : S95 - S95
[32] The effect of hepatitis B virus status of the donor on the hepatitis B virus serology of the recipient after allogeneic hematopoietic cell transplantation
Idilman, R
Soydan, E
Arat, M
Toruner, M
Soykan, I
Karayalcin, S
Ustun, C
Topcuoglu, P
Ozcan, M
Arslan, O
Beksac, M
Ilhan, O
Akan, H
Ozden, A
JOURNAL OF HEPATOLOGY, 2003, 38 : 146 - 146
[33] Reduced therapeutic effect of antiviral drugs in patients with hepatitis B virus reactivation after hematopoietic stem cell transplantation
Kimura, Masamichi
Nishikawa, Koji
Sakamaki, Hisashi
Mizokami, Masashi
Kimura, Kiminori
HEPATOLOGY RESEARCH, 2018, 48 (06) : 469 - 478
[34] Prophylactic antiviral therapy in allogeneic hematopoietic stem cell transplantation in hepatitis B virus patients
Liao, Ya-Ping
Jiang, Jia-Lu
Zou, Wai-Yi
Xu, Duo-Rong
Li, Juan
WORLD JOURNAL OF GASTROENTEROLOGY, 2015, 21 (14) : 4284 - 4292
[35] Prophylactic antiviral therapy in allogeneic hematopoietic stem cell transplantation in hepatitis B virus patients
Ya-Ping Liao
Jia-Lu Jiang
Wai-Yi Zou
Duo-Rong Xu
Juan Li
World Journal of Gastroenterology, 2015, (14) : 4284 - 4292
[36] Screening of hepatitis B virus before hematopoietic cell transplantation
Nakaya, A.
Fujita, S.
Satake, A.
Nakanishi, T.
Azuma, Y.
Tsubokura, Y.
Hotta, M.
Yoshimura, H.
Ishii, K.
Ito, T.
Nomura, S.
BONE MARROW TRANSPLANTATION, 2016, 51 : S581 - S581
[37] Retrospective Study on the Impact of Hepatitis B and Hepatitis C Virus Infection on Hematopoietic Stem Cell Transplantation in Japan
Motohiro Hamaguchi
Hironori Yamad
Hisashi Gondo
Yoshinobu Takemoto
Yasuo Morishima
Yoshihisa Kodera
International Journal of Hematology, 2002, 75 : 324 - 331
[38] Retrospective study on the impact of hepatitis B and hepatitis C virus infection on hematopoietic stem cell transplantation in Japan
Hamaguchi, M
Yamada, H
Gondo, H
Takemoto, Y
Morishima, Y
Kodera, Y
INTERNATIONAL JOURNAL OF HEMATOLOGY, 2002, 75 (03) : 324 - 331
[39] Hepatitis G virus (HGV) - Association with graft failure after hematopoietic stem cell transplantation?
Korn, K
Schmidt, B
Greil, J
Beck, J
Fleckenstein, B
TRANSFUSIONSMEDIZIN 1996/97, 1997, 34 : 16 - 20
[40] Acute hepatitis B after autologous stem cell transplantation in a man previously infected by hepatitis B virus
Senecal, D
Pichon, E
Dubois, F
Delain, M
Linassier, C
Colombat, P
BONE MARROW TRANSPLANTATION, 1999, 24 (11) : 1243 - 1244

← 1 2 3 4 5 →