Reverse seroconversion of hepatitis B virus after hematopoietic stem cell transplantation

被引：40

作者：

Goyama, S ^{[1
]}

Kanda, Y ^{[1
]}

Nannya, Y ^{[1
]}

Kawazu, M ^{[1
]}

Takeshita, M ^{[1
]}

Niino, M ^{[1
]}

Komeno, Y ^{[1
]}

Nakamoto, T ^{[1
]}

Kurokawa, M ^{[1
]}

Tsujino, S ^{[1
]}

Ogawa, S ^{[1
]}

Aoki, K ^{[1
]}

Chiba, S ^{[1
]}

Motokura, T ^{[1
]}

Shiratori, Y ^{[1
]}

Hirai, H ^{[1
]}

机构：

[1] Univ Tokyo, Grad Sch Med, Dept Hematol & Oncol, Bunkyo Ku, Tokyo 1138655, Japan

来源：

LEUKEMIA & LYMPHOMA | 2002年 / 43卷 / 11期

关键词：

hepatitis B virus; reverse seroconversion; hematopoietic stem cell transplantation; immunosuppression;

D O I：

10.1080/1042819021000033042

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Hepatitis B virus (HBV) reactivation in patients previously positive for hepatitis B surface antibody (HBsAb), so-called reverse seroconversion, has been considered to be a rare complication after hematopoietic stem cell transplantation (HSCT). We experienced two patients who developed reverse seroconversion among nine who were HBsAb positive and Hepatitis B core antibody (HBcAb) positive before HSCT; one after autologous bone marrow transplantation (BMT) and another after allogeneic peripheral blood stem cell transplantation (PBSCT). We reviewed the literature and considered that reverse seroconversion of HBV after HSCT is not uncommon among HBsAb positive recipients. The use of corticosteroids, the lack of HBsAb in donor, and a decrease in serum HBsAb and HBcAb levels may predict reverse seroconversion after HSCT.

引用

页码：2159 / 2163

页数：5

共 50 条

[1] Hepatitis B virus reverse seroconversion in allogeneic hematopoietic stem cell transplantation
Vigano, M.
Vener, C.
Soligo, D.
Colombo, M.
Lanfranchi, F.
Deliliers, G. Lambertenghi
Lampertico, P.
JOURNAL OF CLINICAL VIROLOGY, 2006, 36 : S76 - S76
[2] REVERSE SEROCONVERSION OF HEPATITIS B VIRUS (HBV) AFTER ALLOGENIC HEMATOPOIETIC STEM CELL TRANSPLANTATION IN HBV ENDEMIC AREA
Park, S.
Kim, K. H.
Ahn, H. K.
Lee, S. J.
Yi, J. H.
Jung, C. W.
Kim, D. H.
Jang, J. H.
Kim, W. S.
Kim, S. J.
HAEMATOLOGICA-THE HEMATOLOGY JOURNAL, 2010, 95 : 444 - 444
[3] Autoimmune thrombopenia associated with hepatitis B reactivation (reverse seroconversion) after autologous hematopoietic stem cell transplantation
Aubourg, Alexandre
d'Alteroche, Louis
Senecal, Delphine
Gaudy, Catherine
Bacq, Yannick
GASTROENTEROLOGIE CLINIQUE ET BIOLOGIQUE, 2007, 31 (01): : 97 - 99
[4] Hepatitis B Virus (HBV) Reverse Seroconversion after Allogeneic Hematopoietic Stem Cell Transplantation the Impact of Post-Transplant Vaccination
Hammond, Sarah P.
Ho, Vincent T.
Ukomadu, Chinweike
Baden, Lindsey R.
Marty, Francisco M.
HEPATOLOGY, 2013, 58 : 303A - 304A
[5] Hepatitis B reverse seroconversion in long term survivors of allogeneic hematopoietic stem cell transplantation
Le, Quan
Savani, Bipin N.
Shenoy, Aarthi
Kozanas, Eleftheria
Barrett, A. John
BLOOD, 2007, 110 (11) : 588A - 589A
[6] Reverse seroconversion of hepatitis B virus after allogeneic hematopoietic stem cell transplantation in the absence of chronic graft-versus-host disease
Oshima, Kumi
Sato, Miki
Okuda, Shinya
Terasako, Kiriko
Nakasone, Hideki
Kako, Shinichi
Yamazaki, Rie
Tanaka, Yukie
Tanihara, Aki
Higuchi, Takakazu
Nishida, Junji
Nakamura, Ikuo
Yoshida, Yukio
Kanda, Yoshinobu
HEMATOLOGY, 2009, 14 (02) : 73 - 75
[7] SURFACE ANTIGEN SEROCONVERSION AFTER ALLOGENIC HEMATOPOIETIC STEM CELL TRANSPLANTATION IN PATIENT WITH CHRONIC HEPATITIS B VIRUS INFECTION
Woo, Seong Yong
Kim, Chang Wook
Nam, Soon Woo
Choi, Jong Young
Cho, Se Hyun
Yang, Jin Mo
Hon, Joon-Yeol
Lee, Young Suk
HEPATOLOGY, 2008, 48 (04) : 673A - 673A
[8] Progressive disappearance of anti-hepatitis B surface antigen antibody and reverse seroconversion after allogeneic hematopoietic stem cell transplantation in patients with previous hepatitis B virus infection
Onozawa, M
Hashino, S
Izumiyama, K
Kahata, K
Chuma, M
Mori, A
Kondo, T
Toyoshima, N
Ota, S
Kobayashi, S
Hige, S
Toubai, T
Tanaka, J
Imamura, M
Asaka, M
TRANSPLANTATION, 2005, 79 (05) : 616 - 619
[9] Hepatitis B after autologous hematopoietic transplantation. : Description of a case of reverse seroconversion
Sainz, ER
Cachón, RF
Marín, RC
Matilla, BN
Rodríquez, MNF
REVISTA CLINICA ESPANOLA, 2001, 201 (06): : 365 - 366
[10] Lamivudine Prophylaxis and Hepatitis B Vaccination for Prevention of Hepatitis B Virus Reverse Seroconversion in Long-Term Survivors after Allogeneic Stem Cell Transplantation
Le, Quan
Shenoy, Aarthi
Koklanaris, Eleftheria
Childs, Richard
Barrett, A. John
Savani, Bipin N.
BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, 2009, 15 (07) : 886 - 887

← 1 2 3 4 5 →