Microwave synthesis of 2-[(E)-2-(1H-indol-3-yl)vinyl] hetarenes

被引：5
|
作者：
Aksenov, Alexander V. [1 ]
Nadein, Oleg N. [1 ]
Aksenov, Nicolai A. [1 ]
Skomorokhov, Anton A. [1 ]
Aksenova, Inna V. [1 ]
Rubin, Michael A. [1 ,2 ]
机构：
[1] North Caucasus Fed Univ, 1 Pushkin St, Stavropol 355009, Russia
[2] Univ Kansas, 1251 Wescoe Hall Dr, Lawrence, KS 66045 USA
来源：
CHEMISTRY OF HETEROCYCLIC COMPOUNDS | 2015年 / 51卷 / 10期
关键词：
benzoxazole; indole; pyridine; quinoline; condensation; microwave synthesis; CELL IMAGING PROBES; 3-SUBSTITUTED; 2-QUINOLONES; MESSENGER-RNA; STYRYL DYES; IN-VIVO; EXPRESSION; INDOLES; DNA;
D O I：
10.1007/s10593-015-1788-0
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A new highly efficient method for the condensation of (indol-3-yl)carbaldehydes with 2-methylazoles and 2-methylazines under activation with microwave irradiation is developed. The method provides high yields of structural scaffolds of bishetarylethylene fluorescent sensors that found widespread application in medicinal, bioorganic, and pharmaceutical chemistry.
引用
收藏
页码：865 / 868
页数：4
相关论文
共 50 条
  • [21] 2′-[(5-bromo-1H-indol-3-yl)methylene]-2-(1H-indol-3-yl)acetohydrazide ethyl acetate solvate
    Ali, Hapipah M.
    Shimar, Jamaludin Nazzatush
    Ng, Seik Weng
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2007, 63 : O2731 - U1620
  • [22] (E)-2-[(2,4-Dihydroxybenzylidene)azaniumyl]-3-(1H-indol-3-yl)propanoate monohydrate
    Ba-Salamah, Salah Ahmed
    Eltayeb, Naser Eltaher
    Teoh, Siang Guan
    Lo, Kong Mun
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2011, 67 : O2113 - U1219
  • [23] (E)-2-{[1-Carboxy-2-(1H-indol-3-yl)ethyliminio]methyl}-6-hydroxyphenolate
    Ba-Salamah, Salah Ahmed
    Eltayeb, Naser Eltaher
    Teoh, Siang Guan
    Lo, Kong Mun
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2011, 67 : O2389 - U769
  • [24] Synthesis, crystal structure and DFT study of methyl 2-(1H-indol-3-yl)-2-oxoacetate
    Yang, Yan
    Li, Jin-Lan
    Ma, Li-Xue
    Yang, Bai-Hui
    Zhou, Zhi-Xu
    Ji, Chun
    MOLECULAR CRYSTALS AND LIQUID CRYSTALS, 2023, 766 (01) : 90 - 99
  • [25] N′-(2-hydroxy-5-nitrobenzylidene)-2-(1H-indol-3-yl)acetohydrazide
    Puvaneswary, Subramaniam
    Ali, Hapipah M.
    Robinson, Ward T.
    Ng, Seik Weng
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2008, 64 : O1777 - U2123
  • [26] Novel N-Substituted 2-(2-(Adamantan-1-yl)-1H-Indol-3-yl)-2-Oxoacetamide Derivatives: Synthesis and Biological Evaluation
    Hu, Hong-Yu
    Yu, Xu-Dong
    Wang, Fei
    Lin, Chun-Rong
    Zeng, Jin-Zhang
    Qiu, Ying-Kun
    Fang, Mei-Juan
    Wu, Zhen
    MOLECULES, 2016, 21 (05):
  • [27] Aminopalladation-Triggered Carbene Insertion Reaction: Synthesis of 2-(1H-Indol-3-yl)acetates
    Hu, Ziwei
    Luo, Shuang
    Zhu, Qiang
    ADVANCED SYNTHESIS & CATALYSIS, 2015, 357 (05) : 1060 - 1064
  • [28] Synthesis and evaluation of 2-(1H-indol-3-yl)-4-phenylquinolines as inhibitors of cholesterol esterase
    Muscia, Gisela C.
    Hautmann, Stephanie
    Buldain, Graciela Y.
    Asis, Silvia E.
    Guetschow, Michael
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2014, 24 (06) : 1545 - 1549
  • [29] Synthesis of 2-(1H-indol-3-yl)pyridine derivatives through multi-component reaction
    Geng, Li-Jun
    Feng, Guo-Liang
    Yu, Jiu-Gao
    JOURNAL OF CHEMICAL RESEARCH, 2010, (10) : 565 - 567
  • [30] Synthesis, pharmacological screening and computational analysis of some 2-(1H-Indol-3-yl)-N′-[(un)substituted phenylmethylidene]acetohydrazides and 2-(1H-Indol-3-yl)-N′-[(un)substituted benzoy1/2-thienylcarbonyl]acetohydrazides
    Rubab, Kaniz
    Abbasi, Muhammad Athar
    Aziz-ur-Rehman
    Siddiqui, Sabahat Zahra
    Shah, Syed Adnan Ali
    Ashra, Muhammad
    Qurat-ul-Ain
    Ahmad, Irshad
    Lodhi, Muhammad Arif
    Ghufran, Mehreen
    Shahid, Muhammad
    Fatima, Hina
    PAKISTAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2017, 30 (04) : 1263 - 1274
12345