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A rhodamine-based fluorescent probe for Hg2+: synthesis, theoretical calculations and bio-imaging applications
被引:7
|作者:
Zhang, Ming
[1
]
Liu, Xiaojing
[1
]
Bao, Yi
[1
]
Yang, Bingqin
[1
]
机构:
[1] Northwest Univ, Minist Educ, Key Lab Synthet & Nat Funct Mol Chem, Coll Chem & Mat Sci, Xian 710127, Shaan Xi, Peoples R China
来源:
基金:
中国国家自然科学基金;
关键词:
Fluorescent probes;
Fluorescence imaging;
Theoretical calculation;
LIVING CELLS;
MERCURY;
RECOGNITION;
DESIGN;
WATER;
IRON;
SENSORS;
HG(II);
MEDIA;
FE3+;
D O I:
10.1016/j.tet.2015.11.043
中图分类号:
O62 [有机化学];
学科分类号:
070303 ;
081704 ;
摘要:
A novel rhodamine-based fluorescent probe was designed and synthesized. The probe exhibited highly selective and sensitive recognition toward Hg2+ over other metal ions, which can be used for 'naked-eyes' detection. In addition, fluorescence imaging experiments of Hg2+ in living cells and living animal demonstrated their valuable application in biological systems. Meanwhile, we performed theoretical calculations for researching the reaction mechanism between probe and Hg2+. (C) 2015 Elsevier Ltd. All rights reserved.
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页码:328 / 332
页数:5
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