A rhodamine-based fluorescent probe for Hg2+: synthesis, theoretical calculations and bio-imaging applications

被引:7
|
作者
Zhang, Ming [1 ]
Liu, Xiaojing [1 ]
Bao, Yi [1 ]
Yang, Bingqin [1 ]
机构
[1] Northwest Univ, Minist Educ, Key Lab Synthet & Nat Funct Mol Chem, Coll Chem & Mat Sci, Xian 710127, Shaan Xi, Peoples R China
基金
中国国家自然科学基金;
关键词
Fluorescent probes; Fluorescence imaging; Theoretical calculation; LIVING CELLS; MERCURY; RECOGNITION; DESIGN; WATER; IRON; SENSORS; HG(II); MEDIA; FE3+;
D O I
10.1016/j.tet.2015.11.043
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A novel rhodamine-based fluorescent probe was designed and synthesized. The probe exhibited highly selective and sensitive recognition toward Hg2+ over other metal ions, which can be used for 'naked-eyes' detection. In addition, fluorescence imaging experiments of Hg2+ in living cells and living animal demonstrated their valuable application in biological systems. Meanwhile, we performed theoretical calculations for researching the reaction mechanism between probe and Hg2+. (C) 2015 Elsevier Ltd. All rights reserved.
引用
收藏
页码:328 / 332
页数:5
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