Novel substituted piperazines: New chemical class of selective 5-HT6 receptor antagonists

被引:0
|
作者
Shirsath, Vikas S. [1 ]
Deshpande, Amol D. [1 ]
Dwarampudi, Adi R. [1 ]
Bhatta, Venugopala Rao [1 ]
Bhosale, Sandeep B. [1 ]
Kota, Srinivasulu [1 ]
Kandikere, Vishwottam N. [1 ]
Kambhampati, Rama S. [1 ]
Nirogi, Ramakrishna V. S. [1 ]
机构
[1] Suven Life Sci Ltd, Discovery Res, Hyderabad 500034, Andhra Pradesh, India
关键词
D O I
暂无
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
142-MEDI
引用
收藏
页数:1
相关论文
共 50 条
  • [41] 5-HT6 receptor and cognition
    Codony, Xabier
    Miguel Vela, Jose
    Javier Ramirez, Maria
    CURRENT OPINION IN PHARMACOLOGY, 2011, 11 (01) : 94 - 100
  • [42] Benzimidazole Derivatives as New Serotonin 5-HT6 Receptor Antagonists. Molecular Mechanisms of Receptor Inactivation
    de la Fuente, Tania
    Martin-Fontecha, Mar
    Sallander, Jessica
    Benhamu, Bellinda
    Campillo, Mercedes
    Medina, Rocio A.
    Pellissier, Lucie P.
    Claeysen, Sylvie
    Dumuis, Aline
    Pardo, Leonardo
    Lopez-Rodriguez, Maria L.
    JOURNAL OF MEDICINAL CHEMISTRY, 2010, 53 (03) : 1357 - 1369
  • [43] Identification of enantiomerically pure 5-HT6 receptor antagonists by chiral resolution
    Park, Chul Min
    Kang, Sunhee
    Park, Wookyu
    Park, Nosang
    Seong, Churlmin
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2007, 233 : 697 - 697
  • [44] Recent progress in 5-HT6 receptor antagonists for the treatment of CNS diseases
    Slassi, A
    Isaac, M
    O'Brien, A
    EXPERT OPINION ON THERAPEUTIC PATENTS, 2002, 12 (04) : 513 - 527
  • [45] 5-HT6 RECEPTOR CHARACTERTIZATION
    Riccioni, Teresa
    PHARMACOLOGY OF 5-HT6 RECEPTORS, PT 1, 2010, 94 : 67 - 88
  • [46] Serotonin 5-HT6 receptor antagonists for the treatment of Alzheimer's disease
    Geldenhuys, Werner J.
    Van der Schyf, Cornelis J.
    CURRENT TOPICS IN MEDICINAL CHEMISTRY, 2008, 8 (12) : 1035 - 1048
  • [47] Pharmacological profile of a novel and selective 5-HT6 receptor agonist: WAY-466
    Schechter, L. E.
    Smith, D. L.
    Li, P.
    Lin, Q.
    Rosenzweig-Lipson, S.
    Beyer, C. E.
    Robichaud, A.
    Bernotas, R.
    FUNDAMENTAL & CLINICAL PHARMACOLOGY, 2004, 18 : 146 - 146
  • [48] WAY-181187: neurochemical profile of a novel and selective 5-HT6 receptor agonist
    Beyer, CE
    Smith, DL
    Zhang, G
    Li, P
    Lin, Q
    Stock, JR
    Ellingboe, JW
    Bernotas, R
    Cole, DC
    Dawson, LA
    Schechter, LE
    EUROPEAN NEUROPSYCHOPHARMACOLOGY, 2005, 15 : S382 - S382
  • [49] N1-(benzenesulfonyl)tryptamines as novel 5-HT6 antagonists
    Tsai, YC
    Dukat, M
    Slassi, A
    MacLean, N
    Demchyshyn, L
    Savage, JE
    Roth, BL
    Hufesein, S
    Lee, M
    Glennon, RA
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2000, 10 (20) : 2295 - 2299
  • [50] Synthesis and SAR of tolylamine 5-HT6 antagonists
    Singer, Jamie M.
    Wilson, Michael W.
    Johnson, Paul D.
    Graham, Shelley R.
    Cooke, Leonard W.
    Roof, Robin L.
    Boxer, Peter A.
    Gold, Lisa H.
    Meltzer, Leonard T.
    Janssen, Ann
    Roush, Nicole
    Campbell, Jeffrey E.
    Su, Ti-Zhi
    Hurst, Susan I.
    Stoner, Chad L.
    Schwarz, Jacob B.
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2009, 19 (09) : 2409 - 2412