An evaluation of machine-learning methods for predicting pneumonia mortality

被引:103
|
作者
Cooper, GF
Aliferis, CF
Ambrosino, R
Aronis, J
Buchanan, BG
Caruana, R
Fine, MJ
Glymour, C
Gordon, G
Hanusa, BH
Janosky, JE
Meek, C
Mitchell, T
Richardson, T
Spirtes, P
机构
[1] UNIV PITTSBURGH, DEPT COMP SCI, INTELLIGENT SYST LAB, PITTSBURGH, PA 15213 USA
[2] CARNEGIE MELLON UNIV, SCH COMP SCI, PITTSBURGH, PA 15213 USA
[3] UNIV PITTSBURGH, DEPT MED, DIV GEN INTERNAL MED, PITTSBURGH, PA 15213 USA
[4] CARNEGIE MELLON UNIV, DEPT PHILOSOPHY, PITTSBURGH, PA 15213 USA
[5] UNIV PITTSBURGH, DEPT FAMILY MED & CLIN EPIDEMIOL, DIV BIOSTAT, PITTSBURGH, PA 15261 USA
关键词
clinical databases; computer-based prediction; machine learning; pneumonia;
D O I
10.1016/S0933-3657(96)00367-3
中图分类号
TP18 [人工智能理论];
学科分类号
081104 ; 0812 ; 0835 ; 1405 ;
摘要
This paper describes the application of eight statistical and machine-learning methods to derive computer models for predicting mortality of hospital patients with pneumonia from their findings at initial presentation. The eight models were each constructed based on 9847 patient cases and they were each evaluated on 4352 additional cases. The primary evaluation metric was the error in predicted survival as a function of the fraction of patients predicted to survive. This metric is useful in assessing a model's potential to assist a clinician in deciding whether to treat. a given patient in the hospital or at home. We examined the error rates of the models when predicting that a given fraction of patients will survive. We examined survival fractions between 0.1 and 0.6. Over this range, each model's predictive error rate was within 1% of the error rate of every other model. When predicting that approximately 30% of the patients will survive, all the models have an error rate of less than 1.5%. The models are distinguished more by the number of variables and parameters that they contain than by their error rates; these differences suggest which models may be the most amenable to future implementation as paper-based guidelines. Copyright (C) 1997 Elsevier Science B.V.
引用
收藏
页码:107 / 138
页数:32
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