Crystallization and preliminary X-ray analysis of the thymidylate kinase from Mycobacterium tuberculosis

被引：10
|
作者：
de la Sierra, IL
Munier-Lehmann, H
Gilles, AM
Bârzu, O
Delarue, M
机构：
[1] Inst Pasteur, Unite Biochim Struct, F-75724 Paris 15, France
[2] Inst Pasteur, Lab Chim Struct Macromol, F-75724 Paris 15, France
来源：
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY | 2000年 / 56卷
关键词：
D O I：
10.1107/S0907444999016212
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
Mycobacterium tuberculosis thymidylate kinase complexed with the substrate deoxythymidine monophosphate was crystallized in the hexagonal space group P6(5)22 or P6(1)22, with unit-cell parameters a = b = 76.62, c = 134.38 Angstrom and one single monomer of 23 kDa in the asymmetric unit. Cryo-cooled crystals diffract at 1.94 Angstrom resolution using synchrotron radiation.
引用
收藏
页码：226 / 228
页数：3
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