The role of hyaluronan in wound healing

被引:150
|
作者
Frenkel, Joseph S. [1 ]
机构
[1] Cardiff Univ, Sch Med, Dept Wound Healing, Wound Healing Res Unit, Melbourne, Vic, Australia
关键词
Hyaluronan; Clinical application; Dermatology; Wound healing; Wound dressings; INTER-ALPHA-INHIBITOR; SKIN; FRAGMENTS; TSG-6; ACID;
D O I
10.1111/j.1742-481X.2012.01057.x
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
The polysaccharide hyaluronan (HA) (synonyms - hyaluronic acid, hyaluronate) is a versatile, polymorphic, glycosoaminoglycan with vast biological functions. HA is found throughout the body, primarily residing in skin, thus playing an important role in wound healing. Research regarding HA's function has changed over the years, primarily focussing on a particular aspect or function. The contribution of HA in each stage of normal wound healing as well as its clinical wound dressing applications will be examined.
引用
收藏
页码:159 / 163
页数:5
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