Reexamination of respiration-impairing effect of bikaverin on isolated mitochondria

被引:0
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作者
Kitagawa, A
Sugihara, Y
Okumura, M
Kawai, K
Hamasaki, T
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S3 [农学(农艺学)];
学科分类号
0901 ;
摘要
Bikaverin was examined for the respiration-impairing effect, using isolated rat liver mitochondria and submitochondrial particles (SMP). It was concluded that bikaverin repressed both NAD- and succinate-linked respirations at low concentrations, and uncoupled oxidative phosphorylation in consequence of the lysis (swelling) of inner mitochondrial membranes at high concentrations.
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页码:451 / 452
页数:2
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