The cost of Alzheimer's disease in China and re-estimation of costs worldwide

被引：656

作者：

Jia, Jianping ^{[1
,2
,3
,4
,5
]}

Wei, Cuibai ^{[1
]}

Chen, Shuoqi ^{[1
]}

Li, Fangyu ^{[1
]}

Tang, Yi ^{[1
]}

Qin, Wei ^{[1
]}

Zhao, Lina ^{[1
]}

Jin, Hongmei ^{[1
]}

Xu, Hui ^{[1
]}

Wang, Fen ^{[1
]}

Zhou, Aihong ^{[1
]}

Zuo, Xiumei ^{[1
]}

Wu, Liyong ^{[1
]}

Han, Ying ^{[1
]}

Han, Yue ^{[1
]}

Huang, Liyuan ^{[1
]}

Wang, Qi ^{[1
]}

Li, Dan ^{[1
]}

Chu, Changbiao ^{[1
]}

Shi, Lu ^{[1
]}

Gong, Min ^{[1
]}

Du, Yifeng ^{[6
]}

Zhang, Jiewen ^{[7
]}

Zhang, Junjian ^{[8
]}

Zhou, Chunkui ^{[9
]}

Lv, Jihui ^{[10
]}

Lv, Yang ^{[11
]}

Xie, Haiqun ^{[12
]}

Ji, Yong ^{[13
]}

Li, Fang ^{[14
]}

Yu, Enyan ^{[15
]}

Luo, Benyan ^{[16
]}

Wang, Yanjiang ^{[17
]}

Yang, Shanshan ^{[18
]}

Qu, Qiumin ^{[19
]}

Guo, Qihao ^{[20
,21
]}

Liang, Furu ^{[22
]}

Zhang, Jintao ^{[23
]}

Tan, Lan ^{[24
]}

Shen, Lu ^{[25
]}

Zhang, Kunnan ^{[26
]}

Zhang, Jinbiao ^{[27
]}

Peng, Dantao ^{[28
]}

Tang, Muni ^{[29
]}

Lv, Peiyuan ^{[30
]}

Fang, Boyan ^{[31
]}

Chu, Lan ^{[32
]}

Jia, Longfei ^{[33
]}

Gauthier, Serge ^{[34
]}

机构：

[1] Capital Med Univ, Xuan Wu Hosp, Dept Neurol, Beijing, Peoples R China

[2] Beijing Key Lab Geriatr Cognit Disorders, Beijing, Peoples R China

[3] Beijing Inst Brain Disorders, Ctr Alzheimers Dis, Beijing, Peoples R China

[4] Minist Educ, Key Lab Neurodegenerat Dis, Beijing, Peoples R China

[5] Natl Clin Res Ctr Geriatr Disorders, Beijing, Peoples R China

[6] Shandong Univ, Shandong Prov Hosp, Dept Neurol, Jinan, Shandong, Peoples R China

[7] Henan Prov Peoples Hosp, Dept Neurol, Zhengzhou, Henan, Peoples R China

[8] Wuhan Univ, Dept Neurol, Zhongnan Hosp, Wuhan, Hubei, Peoples R China

[9] Jilin Univ, Dept Neurol, Teaching Hosp 1, Changchun, Jilin, Peoples R China

[10] Beijing Geriatr Hosp, Dementia Unit, Beijing, Peoples R China

[11] Chongqing Med Univ, Dept Geriatr, Affiliated Hosp 1, Chongqing, Peoples R China

[12] Sun Yat Sen Univ, Dept Neurol, Affiliated Foshan Hosp, Foshan, Peoples R China

[13] Tianjin Huanhu Hosp, Dept Neurol, Tianjin, Peoples R China

[14] Capital Med Univ, Fuxing Hosp, Dept Gerontol, Beijing, Peoples R China

[15] Zhejiang Prov Peoples Hosp, Dept Psychiat, Hangzhou, Zhejiang, Peoples R China

[16] Zhejiang Univ, Dept Neurol, Affiliated Hosp 1, Hangzhou, Zhejiang, Peoples R China

[17] Third Mil Med Univ, Daping Hosp, Dept Neurol, Chongqing, Peoples R China

[18] Daqing Oilfield Gen Hosp, Dept Neurol, Daqing, Peoples R China

[19] Xi An Jiao Tong Univ, Dept Neurol, Affiliated Hosp 1, Xian, Shaanxi, Peoples R China

[20] Fudan Univ, Huashan Hosp, Dept Neurol, Shanghai, Peoples R China

[21] Fudan Univ, Huashan Hosp, Inst Neurol, Shanghai, Peoples R China

[22] Baotou Cent Hosp, Dept Neurol, Baotou, Peoples R China

[23] 88th Hosp PLA, Dept Neurol, Tai An, Shandong, Peoples R China

[24] Qingdao Univ, Sch Med, Qingdao Municipal Hosp, Dept Neurol, Qingdao, Peoples R China

[25] Cent S Univ, Dept Neurol, Xiangya Hosp, Changsha, Hunan, Peoples R China

[26] Peoples Hosp Jiangxi Prov, Dept Neurol, Nanchang, Jiangxi, Peoples R China

[27] Weihai Municipal Hosp, Dept Neurol, Weihai, Peoples R China

[28] China Japan Friendship Hosp, Dept Neurol, Ctr Geriatr Med, Beijing, Peoples R China

[29] Guangzhou Huiai Hosp, Dept Geriatr Psychiat, Guangzhou, Guangdong, Peoples R China

[30] Hebei Gen Hosp, Dept Neurol, Shijiazhuang, Hebei, Peoples R China

[31] Capital Med Univ, Dept Neurol, Beijing Rehabil Hosp Affiliated, Beijing, Peoples R China

[32] Guizhou Med Univ, Dept Neurol, Affiliated Hosp, Guiyang, Guizhou, Peoples R China

[33] Henry Ford Hosp, Dept Neurol, Detroit, MI 48202 USA

[34] McGill Univ, McGill Ctr Studies Aging, Montreal, PQ, Canada

来源：

ALZHEIMERS & DEMENTIA | 2018年 / 14卷 / 04期

基金：

中国国家自然科学基金;

关键词：

Alzheimer's; Dementia; Cost of illness; Observational study; ECONOMIC-IMPACT; DEVELOPING-COUNTRIES; SOCIETAL COSTS; DEMENTIA; PREVALENCE; SHANGHAI; CARE;

D O I：

10.1016/j.jalz.2017.12.006

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Introduction: The socioeconomic costs of Alzheimer's disease (AD) in China and its impact on global economic burden remain uncertain. Methods: We collected data from 3098 patients with AD in 81 representative centers across China and estimated AD costs for individual patient and total patients in China in 2015. Based on this data, we re-estimated the worldwide costs of AD. Results: The annual socioeconomic cost per patient was US $19,144.36, and total costs were US $167.74 billion in 2015. The annual total costs are predicted to reach US $507.49 billion in 2030 and US $1.89 trillion in 2050. Based on our results, the global estimates of costs for dementia were US $957.56 billion in 2015, and will be US $2.54 trillion in 2030, and US $9.12 trillion in 2050, much more than the predictions by the World Alzheimer Report 2015. Discussion: China bears a heavy burden of AD costs, which greatly change the estimates of AD cost worldwide. (C) 2017 the Alzheimer's Association. Published by Elsevier Inc. All rights reserved.

引用

页码：483 / 491

页数：9

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