Magnetic nanoparticles for magnetic drug targeting

被引:19
|
作者
Lyer, Stefan [1 ]
Singh, Raminder [1 ]
Tietze, Rainer [1 ]
Alexiou, Christoph [1 ]
机构
[1] Univ Hosp Erlangen, ENT Dept, SEON, D-91054 Erlangen, Germany
来源
关键词
imaging; magnetic drug targeting; magnetic nanoparticles; oncology; IRON-OXIDE NANOPARTICLES; MODIFIED SUPERPARAMAGNETIC NANOPARTICLES; BRANCHED TUBE MODEL; FLUID HYPERTHERMIA; CANCER-THERAPY; THERMAL-DECOMPOSITION; FE3O4; NANOPARTICLES; PARTICLE-SIZE; DELIVERY; CELLS;
D O I
10.1515/bmt-2015-0049
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
Nanomedicine and superparamagnetic iron oxide nanoparticles (SPIONs) are thought to have an important impact on medicine in the future. Especially in cancer therapy, SPIONs offer the opportunity of improving the effectivity of the treatment and reduce side effects by magnetic accumulation of SPION-bound chemotherapeutics in the tumor area. Although still some challenges have to be overcome, before the new treatment concept of magnetic drug targeting will reach the patients, substantial progress has been made, and promising results were shown in the last years.
引用
收藏
页码:465 / 475
页数:11
相关论文
共 50 条
  • [41] Numerical Modeling of Magnetic Drug Targeting
    Kopcansky, P.
    Timko, M.
    Hnatic, M.
    Vala, M.
    Arzumanyan, G. M.
    Hayryan, E. A.
    Jancurova, L.
    Jadlovsky, J.
    PHYSICS OF PARTICLES AND NUCLEI LETTERS, 2011, 8 (05) : 502 - 505
  • [42] Open challenges in magnetic drug targeting
    Shapiro, Benjamin
    Kulkarni, Sandip
    Nacev, Aleksander
    Muro, Silvia
    Stepanov, Pavel Y.
    Weinberg, Irving N.
    WILEY INTERDISCIPLINARY REVIEWS-NANOMEDICINE AND NANOBIOTECHNOLOGY, 2015, 7 (03) : 446 - 457
  • [43] Mesoporous magnetic microspheres for drug targeting
    Ruiz-Hernandez, E.
    Lopez-Noriega, A.
    Arcos, D.
    Vallet-Regi, M.
    SOLID STATE SCIENCES, 2008, 10 (04) : 421 - 426
  • [44] Magnetic drug targeting in a permeable microvessel
    Shaw, S.
    Murthy, P. V. S. N.
    Sibanda, P.
    MICROVASCULAR RESEARCH, 2013, 85 : 77 - 85
  • [45] Encapsulation of methotrexate loaded magnetic microcapsules for magnetic drug targeting and controlled drug release
    Chakkarapani, Prabu
    Subbiah, Latha
    Palanisamy, Selvamani
    Bibiana, Arputha
    Ahrentorp, Fredrik
    Jonasson, Christian
    Johansson, Christer
    JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS, 2015, 380 : 285 - 294
  • [46] MAGNETIC DRUG TARGETING .1. INVIVO KINETICS OF RADIOLABELED MAGNETIC DRUG CARRIERS
    PAPISOV, MI
    SAVELYEV, VY
    SERGIENKO, VB
    TORCHILIN, VP
    INTERNATIONAL JOURNAL OF PHARMACEUTICS, 1987, 40 (03) : 201 - 206
  • [47] Magnetic biliary stent targeting to treat hepatoma combining with magnetic nanoparticles
    Wang Jianming
    Du Guangsheng
    Zheng Jianwei
    Xiao Baolai
    Li Hong
    Cheng Haibin
    Zou Shengquan
    JOURNAL OF WUHAN UNIVERSITY OF TECHNOLOGY-MATERIALS SCIENCE EDITION, 2008, 23 (03): : 312 - 315
  • [48] Magnetic biliary stent targeting to treat hepatoma combining with magnetic nanoparticles
    Jianming Wang
    Guangsheng Du
    Jianwei Zheng
    Baolai Xiao
    Hong Li
    Haibin Cheng
    Shengquan Zou
    Journal of Wuhan University of Technology-Mater. Sci. Ed., 2008, 23 : 312 - 315
  • [49] MAGNETIC DRUG TARGETING: DRUG DELIVERY IN LARGE VASCULATURE
    Schmieg, Jaime
    Williams, Alicia
    Vlachos, Pavlos
    PROCEEDINGS OF THE ASME SUMMER BIOENGINEERING CONFERENCE 2008, PTS A AND B, 2009, : 985 - 986
  • [50] Accumulation of Magnetic Nanoparticles Employing High Intensity Focused Ultrasound for Drug Targeting Applications
    Fink, Michael
    George, Benedikt
    Rupitsch, Stefan J.
    Ermert, Helmut
    2018 IEEE INTERNATIONAL ULTRASONICS SYMPOSIUM (IUS), 2018,