Single cell transcriptomics of the T cell response to Mycobacterium Tuberculosis reveals phenotypic diversity within and between infected individuals

被引:0
|
作者
Kirschman, Junghwa Choi [1 ]
Ogongo, Paul [2 ]
Ernst, Joel [2 ]
Altin, John [1 ]
机构
[1] Translat Genom Res Inst TGen, Phoenix, AZ USA
[2] Univ Calif San Francisco UCSF, San Francisco, CA USA
来源
JOURNAL OF IMMUNOLOGY | 2020年 / 204卷 / 01期
关键词
D O I
暂无
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
225.21
引用
收藏
页数:1
相关论文
共 50 条
  • [41] Single-cell analysis reveals Mycobacterium tuberculosis ESX-1-mediated accumulation of permissive macrophages in infected mouse lungs
    Zheng, Weihao
    Borja, Michael
    Dorman, Leah C.
    Liu, Jonathan
    Zhou, Andy
    Seng, Amanda
    Arjyal, Ritwicq
    Sunshine, Sara
    Nalyvayko, Alina
    Pisco, Angela Oliveira
    Rosenberg, Oren S.
    Neff, Norma
    Zha, Beth Shoshana
    SCIENCE ADVANCES, 2025, 11 (03):
  • [42] single-cell transcriptomics of blood reveals a natural killer cell subset depletion in tuberculosis (vol 53, 102686, 2020)
    Cai, Yi
    Dai, Youchao
    Wang, Yejun
    Yang, Qianting
    Guo, Jiubiao
    Wei, Cailing
    Chen, Weixin
    Huang, Huanping
    Zhu, Jialou
    Zhang, Chi
    Zheng, Weidong
    Wen, Zhihua
    Liu, Haiying
    Zhang, Mingxia
    Xing, Shaojun
    Jin, Qi
    Feng, Carl G.
    Chen, Xinchun
    EBIOMEDICINE, 2022, 77
  • [43] T-cell and serological responses to Erp, an exported Mycobacterium tuberculosis protein, in tuberculosis patients and healthy individuals
    Martinez, Valerie
    Carcelain, Guislaine
    Badell, Edgar
    Jouan, Marc
    Mauger, Isabelle
    Sellier, Pierre
    Truffot, Chantal
    Bricaire, Francois
    Arend, Sandra M.
    Ottenhoff, Tom
    Autran, Brigitte
    Gicquel, Brigitte
    BMC INFECTIOUS DISEASES, 2007, 7
  • [44] Single-cell transcriptomics reveals regulators underlying immune cell diversity and immune subtypes associated with prognosis in nasopharyngeal carcinoma
    Chen, Yu-Pei
    Yin, Jian-Hua
    Li, Wen-Fei
    Li, Han-Jie
    Chen, Dong-Ping
    Zhang, Cui-Juan
    Lv, Jia-Wei
    Wang, Ya-Qin
    Li, Xiao-Min
    Li, Jun-Yan
    Zhang, Pan-Pan
    Li, Ying-Qin
    He, Qing-Mei
    Yang, Xiao-Jing
    Lei, Yuan
    Tang, Ling-Long
    Zhou, Guan-Qun
    Mao, Yan-Ping
    Wei, Chen
    Xiong, Ke-Xu
    Zhang, Hong-Bo
    Zhu, Shi-Da
    Hou, Yong
    Sun, Ying
    Dean, Michael
    Amit, Ido
    Wu, Kui
    Kuang, Dong-Ming
    Li, Gui-Bo
    Liu, Na
    Ma, Jun
    CELL RESEARCH, 2020, 30 (11) : 1024 - 1042
  • [45] Single-cell transcriptomics reveals regulators underlying immune cell diversity and immune subtypes associated with prognosis in nasopharyngeal carcinoma
    Yu-Pei Chen
    Jian-Hua Yin
    Wen-Fei Li
    Han-Jie Li
    Dong-Ping Chen
    Cui-Juan Zhang
    Jia-Wei Lv
    Ya-Qin Wang
    Xiao-Min Li
    Jun-Yan Li
    Pan-Pan Zhang
    Ying-Qin Li
    Qing-Mei He
    Xiao-Jing Yang
    Yuan Lei
    Ling-Long Tang
    Guan-Qun Zhou
    Yan-Ping Mao
    Chen Wei
    Ke-Xu Xiong
    Hong-Bo Zhang
    Shi-Da Zhu
    Yong Hou
    Ying Sun
    Michael Dean
    Ido Amit
    Kui Wu
    Dong-Ming Kuang
    Gui-Bo Li
    Na Liu
    Jun Ma
    Cell Research, 2020, 30 : 1024 - 1042
  • [46] Differential Transcriptional Response in Macrophages Infected with Cell Wall Deficient versus Normal Mycobacterium Tuberculosis
    Fu, Yu-Rong
    Gao, Kun-Shan
    Ji, Rui
    Yi, Zheng-Jun
    INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES, 2015, 11 (01): : 22 - 30
  • [47] Ample glycosylation in membrane and cell envelope proteins may explain the phenotypic diversity and virulence in the Mycobacterium tuberculosis complex
    Birhanu, Alemayehu Godana
    Yimer, Solomon Abebe
    Kalayou, Shewit
    Riaz, Tahira
    Zegeye, Ephrem Debebe
    Holm-Hansen, Carol
    Norheim, Gunnstein
    Aseffa, Abraham
    Abebe, Markos
    Tonjum, Tone
    SCIENTIFIC REPORTS, 2019, 9 (1)
  • [48] Ample glycosylation in membrane and cell envelope proteins may explain the phenotypic diversity and virulence in the Mycobacterium tuberculosis complex
    Alemayehu Godana Birhanu
    Solomon Abebe Yimer
    Shewit Kalayou
    Tahira Riaz
    Ephrem Debebe Zegeye
    Carol Holm-Hansen
    Gunnstein Norheim
    Abraham Aseffa
    Markos Abebe
    Tone Tønjum
    Scientific Reports, 9
  • [49] Biophysical informatics reveals distinctive phenotypic signatures and functional diversity of single-cell lineages
    Chan, Trevor J.
    Zhang, Xingjian
    Mak, Michael
    BIOINFORMATICS, 2023, 39 (01)
  • [50] Single-cell transcriptomics reveals a compartmentalized antiviral interferon response in the nasal epithelium of mice
    Wang, Xuefei
    Dong, Meng
    Wu, Xinchao
    Schnepf, Daniel
    Thiel, Julia
    Sun, Wenfei
    Wolfrum, Christian
    Li, Sisi
    Jin, Wenfei
    Staeheli, Peter
    Ye, Liang
    JOURNAL OF VIROLOGY, 2025, 99 (03)