Functional characterisation of an engineered next generation lentivirus vector for the treatment of cystic fibrosis

被引:0
|
作者
Moiseenko, A. [1 ]
Pineault, K. [2 ,3 ]
Sergijenko, A. [2 ,3 ]
Alton, E. W. F. W. [2 ,3 ]
Boyd, A. C. [2 ,4 ]
Davies, J. C. [2 ,3 ]
Gill, D. R. [2 ,3 ]
Griesenbach, U. [2 ,3 ]
Hyde, S. C. [2 ,5 ]
McLachlan, G. [2 ,6 ,7 ]
Hobbie, S. [1 ]
Schuler, M. [1 ]
Maier, U. [1 ]
Thomas, M. U. [1 ]
Mennerich, D. [1 ]
Kreuz, S. [1 ]
机构
[1] Boehringer Ingelheim Pharma GmbH & Co KG, Biberach, Germany
[2] Imperial Coll London, UK Resp Gene Therapy Consortium, London, England
[3] Imperial Coll London, Natl Heart & Lung Inst, London, England
[4] Univ Edinburgh, Ctr Genom & Expt Med, IGMM, Edinburgh, Midlothian, Scotland
[5] Univ Oxford, Nuffield Div Clin Lab Sci, Radcliffe Dept Med, Oxford, England
[6] Univ Edinburgh, Roslin Inst, Easter Bush Campus, Edinburgh, Midlothian, Scotland
[7] Univ Edinburgh, R D SVS, Easter Bush Campus, Edinburgh, Midlothian, Scotland
关键词
D O I
暂无
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
P036
引用
收藏
页码:A39 / A39
页数:1
相关论文
共 50 条
  • [41] Racially equitable diagnosis of cystic fibrosis using next-generation DNA sequencing: a case report
    Shum, Bennett O. V.
    Bennett, Glenn
    Navilebasappa, Akash
    Kumar, R. Kishore
    BMC PEDIATRICS, 2021, 21 (01)
  • [42] IMPROVING NEWBORN SCREENING FOR CYSTIC FIBROSIS USING NEXT GENERATION SEQUENCING TECHNOLOGY: A PROSPECTIVE IMPLEMENTATION STUDY
    Baker, M.
    Moon, J.
    Mochal, S.
    Rock, M. J.
    Modaff, P.
    Farrell, P.
    PEDIATRIC PULMONOLOGY, 2017, 52 : S414 - S414
  • [43] Allelic Heterogeneity of Cystic Fibrosis Gene in Brazil: Comparison of a Next-Generation Sequencing Panel with Next-Generation Complete Gene Sequencing and MLPA Results
    Sitnik, R.
    Minillo, R. M.
    Lara, C. C.
    Oliveira, P. M.
    Francisco, R. S.
    Val, F. C.
    Cervato, M. C.
    Muto, N. H.
    Mangueira, C. L.
    Pinho, J. R.
    JOURNAL OF MOLECULAR DIAGNOSTICS, 2016, 18 (06): : 941 - 941
  • [44] Functional and structural changes in the cystic fibrosis lung following antibiotic treatment for exacerbation
    Horsley, A. R.
    Aziz, Z.
    Macleod, K. A.
    Saunders, C. J.
    Meister, M.
    Tyler, P.
    Dewar, M.
    Gray, R.
    Voase, N.
    Cunningham, S.
    Greening, A. P.
    Davies, J. C.
    Alton, E. W. F. W.
    Hansell, D.
    Innes, J. A.
    THORAX, 2007, 62 : A31 - A31
  • [45] An improved and updated assay for the detection of cystic fibrosis-causing variants in CFTR gene by Next Generation Sequencing
    Hernandez, Carmen
    Perez, Virginia
    Hernandez, Alicia
    Garcia Mayo, Mario
    Lupsor, Andreea
    Montaner, Candela
    Valledor, Ines
    EUROPEAN JOURNAL OF HUMAN GENETICS, 2024, 32 : 1206 - 1207
  • [46] Clinical investigational studies for validation of a next-generation sequencing in vitro diagnostic device for cystic fibrosis testing
    Grosu, Daniel S.
    Hague, Lynda
    Chelliserry, Manjula
    Kruglyak, Kristina M.
    Lenta, Ross
    Klotzle, Brandy
    San, Jonathan
    Goldstein, Wendy M.
    Moturi, Sharmili
    Devers, Patricia
    Woolworth, Julie
    Peters, Eric
    Elashoff, Barbara
    Stoerker, Jay
    Wolff, Daynna J.
    Friedman, Kenneth J.
    Highsmith, W. Edward
    Lin, Erick
    Ong, Frank S.
    EXPERT REVIEW OF MOLECULAR DIAGNOSTICS, 2014, 14 (05) : 605 - 622
  • [47] Targeted Next-Generation Sequencing Effectively Analyzed the Cystic Fibrosis Transmembrane Conductance Regulator Gene in Pancreatitis
    Nakano, Eriko
    Masamune, Atsushi
    Niihori, Tetsuya
    Kume, Kiyoshi
    Hamada, Shin
    Aoki, Yoko
    Matsubara, Yoichi
    Shimosegawa, Tooru
    DIGESTIVE DISEASES AND SCIENCES, 2015, 60 (05) : 1297 - 1307
  • [48] Targeted Next-Generation Sequencing Effectively Analyzed the Cystic Fibrosis Transmembrane Conductance Regulator Gene in Pancreatitis
    Eriko Nakano
    Atsushi Masamune
    Tetsuya Niihori
    Kiyoshi Kume
    Shin Hamada
    Yoko Aoki
    Yoichi Matsubara
    Tooru Shimosegawa
    Digestive Diseases and Sciences, 2015, 60 : 1297 - 1307
  • [49] Plasma Microbial Cell-Free DNA Metagenomic Next-Generation Sequencing in People With Cystic Fibrosis
    Wasserman, Mollie G.
    Greenberg, Jonathan
    Hall, Brandon
    Staffa, Steven J.
    Sawicki, Gregory S.
    Priebe, Gregory P.
    PEDIATRIC PULMONOLOGY, 2025, 60 (01)
  • [50] Improving newborn screening for cystic fibrosis using next-generation sequencing technology: a technical feasibility study
    Baker, Mei W.
    Atkins, Anne E.
    Cordovado, Suzanne K.
    Hendrix, Miyono
    Earley, Marie C.
    Farrell, Philip M.
    GENETICS IN MEDICINE, 2016, 18 (03) : 231 - 238