What can one learn from experiments about the elusive transition state?

被引：25

作者：

Chang, I

Cieplak, M ^{[1
]}

Banavar, JR

Maritan, A

机构：

[1] Polish Acad Sci, Inst Phys, PL-02668 Warsaw, Poland

[2] Penn State Univ, Dept Phys, University Pk, PA 16802 USA

[3] Pusan Natl Univ, Natl Res Lab Computat Prote & Biophys, Dept Phys, Pusan 609735, South Korea

[4] Univ Padua, INFM, I-35131 Padua, Italy

[5] Univ Padua, Dipartimento Fis G Galilei, I-35131 Padua, Italy

[6] Abdus Salam Int Ctr Theoret Phys, I-34100 Trieste, Italy

来源：

PROTEIN SCIENCE | 2004年 / 13卷 / 09期

关键词：

protein folding; transition state; protein engineering;

D O I：

10.1110/ps.04713804

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

We present the results of an exact analysis of a model energy landscape of a protein to clarify the idea of the transition state and the physical meaning of the phi values determined in protein engineering experiments. We benchmark our findings to various theoretical approaches proposed in the literature for the identification and characterization of the transition state.

引用

页码：2446 / 2457

页数：12

共 50 条

[11] What can we learn about laser-induced plasmas from Thomson scattering experiments
Dzierzega, K.
Mendys, A.
Pokrzywka, B.
SPECTROCHIMICA ACTA PART B-ATOMIC SPECTROSCOPY, 2014, 98 : 76 - 86
[12] WHAT CAN WE LEARN ABOUT CRITICAL MAGNETIC PHENOMENA FROM MUON SPIN ROTATION EXPERIMENTS
HERLACH, D
FURDERER, K
FAHNLE, M
SCHIMMELE, L
HYPERFINE INTERACTIONS, 1986, 31 (1-4): : 287 - 301
[13] What Can the Church Learn from the Democratic State?
Maier, Hans
INTERNATIONALE KATHOLISCHE ZEITSCHRIFT COMMUNIO, 2022, (04): : 468 - 475
[14] WHAT PHILOSOPHERS KNOW AND WHAT ONE CAN LEARN FROM THEM
Leist, Anton
DEUTSCHE ZEITSCHRIFT FUR PHILOSOPHIE, 2012, 60 (06): : 1030 - 1033
[15] What can we learn (and not learn) from thought experiments in black hole thermodynamics?
Rawad El Skaf
Patricia Palacios
Synthese, 200
[16] WHAT CAN USA LEARN FROM JAPAN ABOUT AGING
PALMORE, E
GERONTOLOGIST, 1975, 15 (01): : 64 - 67
[17] WHAT CAN WE LEARN ABOUT PICTURES FROM THE BLIND
KENNEDY, JM
AMERICAN SCIENTIST, 1983, 71 (01) : 19 - 26
[18] What can Sociology Learn from History about Methodology?
Baur, Nina
HISTORICAL SOCIAL RESEARCH-HISTORISCHE SOZIALFORSCHUNG, 2008, 33 (03): : 217 - 248
[19] What can we learn (and not learn) from thought experiments in black hole thermodynamics?
El Skaf, Rawad
Palacios, Patricia
SYNTHESE, 2022, 200 (06)
[20] What Can We Learn about Teaching from MOOCs?
Falkner, Katrina
17TH KOLI CALLING INTERNATIONAL CONFERENCE ON COMPUTING EDUCATION RESEARCH (KOLI CALLING 2017), 2017, : 1 - 1

← 1 2 3 4 5 →