Tumor-associated trypsin inhibitor

被引:0
|
作者
Stenman, UH [1 ]
机构
[1] Univ Helsinki, Cent Hosp, Dept Clin Chem, Biomedicum, FIN-00029 Helsinki, Finland
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暂无
中图分类号
R446 [实验室诊断]; R-33 [实验医学、医学实验];
学科分类号
1001 ;
摘要
Tumor-associated trypsin inhibitor (TATI) is a low-molecular-weight (6 kDa) trypsin inhibitor that has been used as a marker for ovarian cancer. It is also expressed together with tumor-associated trypsin by many other tumors, and increased serum concentrations of TATI occur in connection with these. TATI is a prognostic marker for ovarian, bladder, and kidney cancer, which may be associated with the participation of trypsin in protease cascades contributing to tumor invasiveness. (C) 2002 American Association for Clinical Chemistry.
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页码:1206 / 1209
页数:4
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