Setaria digitata in advancing our knowledge of human lymphatic filariasis

被引：20

作者：

Perumal, A. N. I. ^{[1
]}

Gunawardene, Y. I. N. S. ^{[2
]}

Dassanayake, R. S. ^{[1
]}

机构：

[1] Univ Colombo, Fac Sci, Dept Chem, Colombo, Sri Lanka

[2] Univ Kelaniya, Fac Med, Mol Med Unit, Ragama, Sri Lanka

来源：

JOURNAL OF HELMINTHOLOGY | 2016年 / 90卷 / 02期

关键词：

MITOCHONDRIA-LIKE PARTICLES; WUCHERERIA-BANCROFTI INFECTION; FUMARATE REDUCTASE SYSTEM; NEMATODE-SPECIFIC PROTEIN; CEREBROSPINAL NEMATODIASIS; PARASITE; WOLBACHIA; ANTIGENS; SURFACE; CATTLE;

D O I：

10.1017/S0022149X15000309

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

Setaria digitata is a filarial parasite that causes fatal cerebrospinal nematodiasis in goats, sheep and horses, resulting in substantial economic losses in animal husbandry in the tropics. Due to its close resemblance to Wuchereria bancrofti, this nematode is also frequently used as a model organism to study human lymphatic filariasis. This review highlights numerous insights into the morphological, histological, biochemical, immunological and genetic aspects of S. digitata that have broadened our understanding towards the control and eradication of filarial diseases.

引用

页码：129 / 138

页数：10

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