Safety and efficacy evaluation of long-course neoadjuvant chemoradiotherapy plus tislelizumab followed by total mesorectal excision for locally advanced rectal cancer: Intermediate results of a multicenter, phase II study

被引：0
|
作者：
Yang, Z. [1 ]
Gao, J. [1 ]
Zhang, X. [1 ]
Wu, G. [1 ]
Deng, W. [1 ]
Liu, Y. [1 ]
Zhang, J. [2 ]
Chen, G. [3 ]
Xu, R. [3 ]
Han, J. [4 ]
Li, A. [5 ]
Liu, G. [6 ]
Sun, Y. [7 ]
Kong, D. [8 ]
Bai, Z. [1 ]
Yao, H. [1 ]
Zhang, Z. [1 ]
机构：
[1] Capital Med Univ, Beijing Friendship Hosp, Dept Gen Surg, Beijing, Peoples R China
[2] Capital Med Univ, Beijing Friendship Hosp, Dept Radiol, Beijing, Peoples R China
[3] Capital Med Univ, Beijing Friendship Hosp, Dept Pathol, Beijing, Peoples R China
[4] Capital Med Univ, Beijing Chaoyang Hosp, Dept Gen Surg, Beijing, Peoples R China
[5] Capital Med Univ, Xuanwu Hosp, Dept Gen Surg, Beijing, Peoples R China
[6] Tianjin Med Univ Gen Hosp, Dept Gen Surg, Tianjin, Peoples R China
[7] Tianjin Peoples Hosp, Dept Anorectal, Tianjin, Peoples R China
[8] TMUCIH, Dept Colorectal Canc, Tianjin, Peoples R China
来源：
ANNALS OF ONCOLOGY | 2022年 / 33卷
关键词：
D O I：
10.1016/j.annonc.2022.10.079
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
47P
引用
收藏
页码：S1447 / S1447
页数：1
相关论文
共 50 条
  • [31] Multicenter phase II trial of transanal total mesorectal excision for rectal cancer: preliminary results
    Patricia Sylla
    Dana Sands
    Alison Ricardo
    Antoinette Bonaccorso
    Alexandros Polydorides
    Mariana Berho
    John Marks
    Justin Maykel
    Karim Alavi
    Karen Zaghiyan
    Mark Whiteford
    Elisabeth Mclemore
    Sami Chadi
    Sherief F. Shawki
    Scott Steele
    Alessio Pigazzi
    Matthew Albert
    Teresa DeBeche-Adams
    Erin Moshier
    Steven D. Wexner
    Surgical Endoscopy, 2023, 37 : 9483 - 9508
  • [32] Prognostic ability of the neoadjuvant rectal(NAR) score in long-course concurrent chemoradiotherapy for patients with locally advanced rectal cancer: a retrospective cohort study
    Siyi Lu
    Ran Peng
    Xianan Li
    Zhaoyu Chen
    Yi Zhou
    Ruize Qu
    Xin Zhou
    Qiuxiang Zhang
    Yuxia Wang
    Xuemin Li
    Tao Sun
    Hao Wang
    Wei Fu
    Malignancy Spectrum, 2024, 1 (01) : 53 - 63
  • [33] A Prospective Observational Study Comparing Long-Course Conventional Neoadjuvant Chemoradiotherapy with Short-Course Radiotherapy Followed by Consolidation Chemotherapy with Delayed Surgery in Locally Advanced Rectal Cancer
    Thakur, Niketa
    Seam, Rajeev K.
    Gupta, Manoj K.
    Gupta, Manish
    Fotedar, Vikas
    Vats, Siddharth
    Rana, Sakshi
    Vias, Poorva
    Ahuja, Rachit
    SOUTH ASIAN JOURNAL OF CANCER, 2020, 9 (02) : 80 - 85
  • [34] Results of a prospective phase II study of total neoadjuvant therapy for locally advanced rectal cancer
    Ma, Huiying
    Tang, Yuan
    Zhang, Wenjue
    Zhou, Haitao
    Liu, Zheng
    Zhang, Haizeng
    Cai, Yong
    Li, Yongheng
    Wei, Lichun
    Liu, Shixin
    Wang, Wenling
    Song, Yongwen
    Chen, Bo
    Lu, Ningning
    Qi, Shunan
    Liu, Yueping
    Wang, Shulian
    Wang, Xishan
    Li, Yexiong
    Jin, Jing
    JOURNAL OF CLINICAL ONCOLOGY, 2024, 42 (3_SUPPL) : 147 - 147
  • [35] Construction and validation of a progression prediction model for locally advanced rectal cancer patients received neoadjuvant chemoradiotherapy followed by total mesorectal excision based on machine learning
    Hu, Jitao
    Sheng, Yuanyuan
    Ma, Jinlong
    Tang, Yujie
    Liu, Dong
    Zhang, Jianqing
    Wei, Xudong
    Yang, Yang
    Liu, Yueping
    Zhang, Yongqiang
    Wang, Guiying
    FRONTIERS IN ONCOLOGY, 2024, 13
  • [36] A multicenter phase II study on the feasibility and efficacy of neoadjuvant chemotherapy for locally advanced rectal cancer.
    Goto, Saori
    Hasegawa, Suguru
    Matsumoto, Takuya
    Hida, Koya
    Kawamura, Junichiro
    Yamanokuchi, Satoshi
    Yamaguchi, Takashi
    Matsusue, Ryo
    Kadokawa, Yoshio
    Kato, Shigeru
    Manaka, Dai
    Nishitai, Ryuta
    Nomura, Akinari
    Kanazawa, Akiyoshi
    Kawada, Kenji
    Kyogoku, Takahisa
    Sakai, Yoshiharu
    JOURNAL OF CLINICAL ONCOLOGY, 2016, 34 (04)
  • [37] Total neoadjuvant approach with FOLFOXIRI plus bevacizumab followed by chemoradiotherapy plus bevacizumab in locally advanced rectal cancer: the TRUST trial
    Masi, Gianluca
    Vivaldi, Caterina
    Fornaro, Lorenzo
    Lonardi, Sara
    Buccianti, Piero
    Sainato, Aldo
    Marcucci, Lorenzo
    Martignetti, Angelo
    Urso, Emanuele Damiano Luca
    Castagna, Maura
    Fontanini, Gabriella
    Bergamo, Francesca
    Musettini, Gianna
    Urbani, Lucio
    Sensi, Elisa
    Balestri, Riccardo
    Montrone, Sabrina
    Pasqualetti, Francesco
    Cremolini, Chiara
    Di Paolo, Antonello
    Zagonel, Vittorina
    Falcone, Alfredo
    EUROPEAN JOURNAL OF CANCER, 2019, 110 : 32 - 41
  • [38] Total neoadjuvant therapy (TnT) with FOLFOX followed by short course radiation in locally advanced rectal cancer: A phase II study.
    Zhao, Janice
    Gim, Gahyun
    Baran, Andrea M.
    Wang, Wenjia
    Zittel, Jason
    Hezel, Aram F.
    Ramsdale, Erika E.
    Badri, Nabeel
    Mcgreevy, Maria
    Qiu, Haoming
    Mulkerin, Daniel
    Temple, Larissa K. F.
    Cellini, Christina
    Fleming, Fergal J.
    Noel, Marcus Smith
    Dunne, Richard Francis
    JOURNAL OF CLINICAL ONCOLOGY, 2024, 42 (3_SUPPL) : 122 - 122
  • [39] Long Term Efficacy of Preoperative Chemotherapy or Chemoradiotherapy Combined with Total Mesorectal Excision for Locally Advanced Rectal Cancer: Retrospective Analysis of 305 Patients
    Abulimiti, M.
    Jin, J.
    Liu, W., Jr.
    Li, S.
    Tang, Y.
    Li, N.
    Tang, Y.
    Wang, S.
    Song, Y.
    Liu, Y.
    Fang, H.
    Lu, N.
    Qi, S.
    Chen, B.
    Li, Y.
    INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2019, 105 (01): : E179 - E180
  • [40] Prognostic Significance of Neoadjuvant Rectal Scores in Preoperative Short-Course Radiotherapy and Long-Course Concurrent Chemoradiotherapy for Patients with Locally Advanced Rectal Cancer
    Huang, Wen-Shih
    Kuan, Feng-Che
    Lin, Meng-Hung
    Chen, Miao-Fen
    Chen, Wen-Cheng
    ANNALS OF SURGICAL ONCOLOGY, 2020, 27 (11) : 4309 - 4318
12345