A novel synthesis of 3-halo-2-phenylquinoline-4-carboxylic acids

被引：6

作者：

Raveglia, LF

Giardina, GAM

Grugni, M

Rigolio, R

Farina, C

机构：

[1] Department of Chemistry, SmithKline Beecham S.p.A, 20021-Baranzate (Milano), Via Zambeletti

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 1997年 / 34卷 / 02期

关键词：

D O I：

10.1002/jhet.5570340235

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The 3-chloro and 3-bromo-2-phenylquinoline-4-carboxylic acids were obtained in good yields through a novel procedure, entailing the synthesis of the 3-amino intermediate and the subsequent replacement of the amino group with chlorine or bromine, according to the Sandmeyer reaction.

引用

页码：557 / 559

页数：3

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