Numerical simulation of corneal transport processes

被引：12

作者：

Li, Long-yuan ^{[1
]}

Tighe, Brian ^{[1
]}

机构：

[1] Aston Univ, Sch Engn & Appl Sci, Birmingham B4 7ET, W Midlands, England

来源：

JOURNAL OF THE ROYAL SOCIETY INTERFACE | 2006年 / 3卷 / 07期

关键词：

corneal swelling; hydration; ionic transport; electrolyte; thermodynamics;

D O I：

10.1098/rsif.2005.0085

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

This paper presents a numerical study on the transport of ions and ionic solution in human corneas and the corresponding influences on corneal hydration. The transport equations for each ionic species and ionic solution within the corneal stroma are derived based on the transport processes developed for electrolytic solutions, whereas the transport across epithelial and endothelial membranes is modelled by using phenomenological equations derived from the thermodynamics of irreversible processes. Numerical examples are provided for both human and rabbit corneas, from which some important features are highlighted.

引用

页码：303 / 310

页数：8

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