Strategies for the selective synthesis of monosubstituted (dichloromethylene)bisphosphonate esters

被引：17
|
作者：
Ahlmark, MJ
Vepsalainen, JJ
机构：
[1] Univ. Kuopio, Dept. Chem., FIN 70211, Kuopio
来源：
TETRAHEDRON | 1997年 / 53卷 / 47期
关键词：
D O I：
10.1016/S0040-4020(97)10073-4
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Strategies for the selective synthesis of monosubstituted (dichloromethylene)bisphosphonate esters {Cl2C[P(O)(OR)((ONa+)-Na-.)][P(O)((ONa+)-Na-.)(2)], where R = Pr, Pr-i, Hex, Ph} starting from monophosphorus species or from symmetric/unsymmetric H2MBP or Cl2MBP tetraester compounds, including the preparation of mixed tetraesters, are described and compared. (C) 1997 Elsevier Science Ltd.
引用
收藏
页码：16153 / 16160
页数：8
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