Successful treatment of gastric cancer after complete response of lung cancer by nivolumab: a case report

被引:2
|
作者
Endo, Shunji [1 ]
Fujiwara, Yoshinori [1 ]
Kurose, Koji [2 ]
Higashida, Masaharu [1 ]
Kubota, Hisako [1 ]
Okamoto, Yuko [1 ]
Mineta, Shumei [1 ]
Tanaka, Hironori [1 ]
Okada, Toshimasa [1 ]
Tsuruta, Atsushi [1 ]
Akiyama, Takashi [3 ]
Oga, Toru [2 ]
Ueno, Tomio [1 ]
机构
[1] Kawasaki Med Sch, Dept Digest Surg, 577 Matsushima, Kurashiki, Okayama 7010192, Japan
[2] Kawasaki Med Sch, Dept Resp Med, 577 Matsushima, Kurashiki, Okayama 7010192, Japan
[3] Kawasaki Med Sch, Dept Pathol, 577 Matsushima, Kurashiki, Okayama 7010192, Japan
关键词
Stomach neoplasms; Lung neoplasms; Laparoscopic gastrectomy; Nivolumab;
D O I
10.1186/s40792-020-01053-y
中图分类号
R61 [外科手术学];
学科分类号
摘要
Background Nivolumab is effective for gastric cancer and lung cancer, but complete response is rare. We experienced a case of synchronous gastric cancer and lung cancer who was treated by nivolumab and laparoscopic gastrectomy. Case presentation A 63-year-old male consulted our institution and was found to have gastric cancer cT1(SM)N0M0 Stage IA and lung cancer cT2N2M1(PUL) Stage IV. He received eight chemotherapy treatments plus radiation, but the lung disease remained progressive. Finally, he received nivolumab therapy and complete response of both cancers was obtained. The gastric cancer recurred, but was successfully treated by laparoscopic gastrectomy. The resected specimen revealed three lesions, each being pT1aN0M0 Stage IA. The primary gastric cancer seemed to have completely vanished without scarring. Conclusions This was thought to be a rare case of gastric cancer recurrence after complete response of gastric cancer and lung cancer to nivolumab.
引用
收藏
页数:6
相关论文
共 50 条
  • [21] Conversion surgery for gastric remnant cancer with liver metastasis after nivolumab combination chemotherapy achieving pathological complete response: a case report and literature review
    Katsumata, Kaori
    Morimoto, Yosuke
    Aoyama, Junya
    Yamada, Toru
    Katsuki, Yusuke
    Nishiyama, Ryo
    Egawa, Tomohisa
    SURGICAL CASE REPORTS, 2024, 10 (01):
  • [22] Durable Complete Radiological Response to Nivolumab in Two Heavily Pretreated Western Elderly Patients With Metastatic Gastric Cancer: A Case Report
    Tirino, Giuseppe
    Petrillo, Angelica
    Pompella, Luca
    Pappalardo, Annalisa
    Laterza, Maria Maddalena
    Panarese, Iacopo
    Sabetta, Rosalaura
    Franco, Renato
    Galizia, Gennaro
    Ciardiello, Fortunato
    De Vita, Ferdinando
    FRONTIERS IN ONCOLOGY, 2020, 10
  • [23] Complete response induced by nivolumab monotherapy in gastric neuroendocrine carcinoma: a case report
    Onishi, Misa
    Furuta, Mitsuhiro
    Yoshioka, Emi
    Yamada, Takanobu
    Hama, Takanori
    Furusawa, Kyoko
    Hayashi, Kei
    Inokuchi, Yasuhiro
    Machida, Nozomu
    Furuse, Junji
    Maeda, Shin
    INTERNATIONAL CANCER CONFERENCE JOURNAL, 2024, 13 (03): : 319 - 324
  • [24] Successful treatment with nivolumab in a patient with gastric cancer with severe liver failure resulting from multiple liver metastases: A case report
    Ikejiri, Fumiyoshi
    Yokomizo, Kanako
    Tamura, Kenji
    ONCOLOGY LETTERS, 2024, 27 (06)
  • [25] A Case of Pathologically Complete Response After Nivolumab Combined with Chemotherapy in a Gastric Cancer Patient with Virchow's Lymph Node Metastasis
    Izumo, Wataru
    Hosoda, Kei
    Kuramochi, Hidekazu
    Nakajima, Go
    Maeda, Shinsuke
    Ito, Shunichi
    Nagashima, Yoji
    Itabashi, Michio
    CLINICAL AND EXPERIMENTAL GASTROENTEROLOGY, 2023, 16 : 107 - 115
  • [26] Diffuse Cystic Metastases in the Lung after Nivolumab Treatment in a Patient with Non-Small Cell Lung Cancer: A Case Report
    Muto, Satoshi
    Ozaki, Yuki
    Inoue, Takuya
    Okabe, Naoyuki
    Matsumura, Yuki
    Hasegawa, Takeo
    Shio, Yutaka
    Suzuki, Hiroyuki
    CASE REPORTS IN ONCOLOGY, 2021, 14 (01): : 34 - 38
  • [27] A case of gastric cancer that developed thrombocytopenia during treatment with nivolumab
    Takehiro Kagaya
    Naohiko Koide
    Yoshinori Koyama
    Yuka Kagaya
    Clinical Journal of Gastroenterology, 2021, 14 : 725 - 729
  • [28] A case of gastric cancer that developed thrombocytopenia during treatment with nivolumab
    Kagaya, Takehiro
    Koide, Naohiko
    Koyama, Yoshinori
    Kagaya, Yuka
    CLINICAL JOURNAL OF GASTROENTEROLOGY, 2021, 14 (03) : 725 - 729
  • [29] Pathological Complete Response and Successful Conversion Surgery After Nivolumab Therapy for Stage IV Oesophagogastric Junction Cancer
    Kumamoto, Tsutomu
    Tomita, Toshihiko
    Hojo, Yudai
    Nakamura, Tatsuro
    Kurahashi, Yasunori
    Ishida, Yoshinori
    Miwa, Hiroto
    Hirota, Seiichi
    Shinohara, Hisashi
    IN VIVO, 2021, 35 (04): : 2247 - 2251
  • [30] Hyperprogressive Disease in the Irradiation Field after a Single Dose of Nivolumab for Gastric Cancer: A Case Report
    Ogata, Takatsugu
    Satake, Hironaga
    Ogata, Misato
    Hatachi, Yukimasa
    Yasui, Hisateru
    CASE REPORTS IN ONCOLOGY, 2018, 11 (01): : 143 - 150