Complete genome analysis of human enterovirus B73 isolated from an acute flaccid paralysis patient in Shandong, China

被引:7
|
作者
Liu, Xiaolin [1 ,2 ]
Tao, Zexin [1 ,2 ]
Wang, Haiyan [1 ,2 ]
Lin, Xiaojuan [1 ,2 ]
Song, Lizhi [1 ,2 ]
Li, Yan [1 ,2 ]
Zhang, Li [1 ,2 ]
Wang, Suting [1 ,2 ]
Cui, Ning [3 ]
Xu, Aiqiang [1 ,2 ,4 ]
Song, Yanyan [4 ]
机构
[1] Shandong Ctr Dis Control & Prevent, Shandong Prov Key Lab Infect Dis Control & Preven, Jinan, Peoples R China
[2] Shandong Univ, Acad Prevent Med, Jinan 250100, Peoples R China
[3] Shandong Univ Tradit Chinese Med, Dept Prevent Med, Coll Basic Med Sci, Jinan, Peoples R China
[4] Shandong Univ, Sch Publ Hlth, Jinan 250012, Peoples R China
关键词
Human enterovirus B73; Genome; Phylogenetic analysis; Recombination; MOLECULAR-IDENTIFICATION; SEQUENCE; INDIA;
D O I
10.1007/s11262-014-1077-5
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
Human enterovirus B73 (EV-B73) is a member of species Enterovirus B. To date, only one complete genome sequence of prototype strain CA55-1988 from California has been available. In this study, the complete genome analysis of an EV-B73 strain 088/SD/CHN/04 isolated from an acute flaccid paralysis case in Shandong Province, China in 2004 is conducted. It had 75.6 and 79.3 % nucleotide similarity with prototype strain CA55-1988 in the VP1 coding region and the complete genome, respectively. It had great VP1 nucleotide divergence (16.7-24.4 %) with EV-B73 strains from other parts of the world. Similarity plot and bootscanning analyses provided evidence of recombination with other EV-B viruses.
引用
收藏
页码:38 / 44
页数:7
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