Solanum incanum extract enhances wound healing and tissue regeneration in burn mice model

被引：6
|
作者：
Qureshi, Zainab [1 ]
Khan, Taous [1 ]
Shah, Abdul Jabbar [1 ]
Wahid, Fazli [2 ]
机构：
[1] COMSATS Univ Islamabad, Dept Pharm, Abbottabad Campus 22060, Islamabad, Pakistan
[2] COMSATS Univ Islamabad, Biotechnol Program, Dept Environm Sci, Abbottabad Campus 22060, Islamabad, Pakistan
来源：
BANGLADESH JOURNAL OF PHARMACOLOGY | 2019年 / 14卷 / 02期
关键词：
COLLAGEN; SKIN;
D O I：
10.3329/bjp.v14i2.40098
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
This study was conducted to evaluate the topical efficacy of Solanum incanum for the treatment of partial-thickness burn in mice model. Mice were treated with topical ointment of S. incanum three times daily for 14 days. The wound healing was observed through wound contraction and histological parameters. The group treated with S. incanum ointment showed 81% reduction in wound area as compared to negative control where wound area reduced to 22%. The histological analysis further confirmed that ointment favors the tissue regeneration and reepithelization thus heal wound rapidly as compared to other groups. In conclusion, S. incanum extract enhances wound healing and tissue regeneration.
引用
收藏
页码：101 / 106
页数：6
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