Four-component reaction of cyclic amines, 2-aminobenzothiazole, aromatic aldehydes and acetylenedicarboxylate

被引：10
|
作者：
Gao, Hong [1 ]
Sun, Jing [1 ]
Yan, Chao-Guo [1 ]
机构：
[1] Yangzhou Univ, Coll Chem & Chem Engn, Yangzhou 225002, Peoples R China
来源：
BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY | 2013年 / 9卷
基金：
中国国家自然科学基金;
关键词：
benzothiazole; domino reaction; electron-deficient alkyne; multicomponent reaction; pyrrolidinone; QUINOLINE-DMAD ZWITTERION; MULTICOMPONENT SYNTHESIS; FACILE SYNTHESIS; DIALKYL ACETYLENEDICARBOXYLATES; 1,4-DIPOLAR CYCLOADDITION; 3-COMPONENT REACTION; EFFICIENT SYNTHESIS; METHYL PROPIOLATE; DOMINO REACTIONS; ARYLAMINES;
D O I：
10.3762/bjoc.9.330
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The four-component reaction of 2-aminobenzothiazole, aromatic aldehydes, acetylenedicarboxylate and piperidine or pyrrolidine in ethanol afforded the functionalized 2-pyrrolidinones containing both benzothiazolyl and piperidinyl (or pyrrolidinyl) units in good yields. On the other hand, the similar four-component reactions resulted in the functionalized morpholinium or piperidinium 2-pyrrolidinon-3-olates in the presence of p-toluenesulfonic acid.
引用
收藏
页码：2934 / 2939
页数：6
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