Population Pharmacokinetics of Abacavir in Pregnant Women

被引：10

作者：

Fauchet, Floris ^{[1
,2
]}

Treluyer, Jean-Marc ^{[1
,2
,3
,4
]}

Preta, Laure-Helene ^{[1
]}

Valade, Elodie ^{[1
,2
]}

Pannier, Emmanuelle ^{[5
]}

Urien, Saik ^{[1
,2
,4
]}

Hirt, Deborah ^{[1
,2
,3
,4
]}

机构：

[1] Univ Paris 05, EA 08, Sorbonne Paris Cite, Paris, France

[2] Hop Tarnier, AP HP, Unite Rech Clin, Paris, France

[3] Grp Hosp Paris Ctr, AP HP, Serv Pharmacol Clin, Paris, France

[4] INSERM, CIC 0901, Paris, France

[5] Grp Hospi, Paris Ctr, Serv Gynecol Obstet, Maternite Port Royal, Paris, France

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2014年 / 58卷 / 10期

关键词：

HIV-INFECTED INFANTS; ZIDOVUDINE; PHARMACODYNAMICS; LAMIVUDINE; INDINAVIR; EFAVIRENZ; ADULTS; MODEL;

D O I：

10.1128/AAC.03469-14

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

For the first time, a population approach was used to describe abacavir (ABC) pharmacokinetics in HIV-infected pregnant and nonpregnant women. A total of 266 samples from 150 women were obtained. No covariate effect (from age, body weight, pregnancy, or gestational age) on ABC pharmacokinetics was found. Thus, it seems unnecessary to adapt the ABC dosing regimen during pregnancy.

引用

页码：6287 / 6289

页数：3

共 50 条

[41] Impact of pregnancy on abacavir pharmacokinetics
Best, BM
Mirochnick, M
Capparelli, EV
Stek, A
Burchett, SK
Holland, DT
Read, JS
Smith, E
Hu, CC
Spector, SA
Connor, JD
AIDS, 2006, 20 (04) : 553 - 560
[42] Abacavir pharmacokinetics in hepatic dysfunction
Wyles, DL
Gerber, JG
CLINICAL INFECTIOUS DISEASES, 2005, 40 (06) : 909 - 910
[43] Abacavir pharmacokinetics during pregnancy
Best, B
Capparelli, EV
Stek, A
Burchett, S
Read, J
Smith, E
Hu, C
Gardella, J
Elgie, C
Schiffhauer, J
Mirochnick, M
JOURNAL OF CLINICAL PHARMACOLOGY, 2004, 44 (10): : 1199 - 1199
[44] THE PHARMACOKINETICS OF MECILLINAM AND PIVMECILLINAM IN PREGNANT AND NONPREGNANT WOMEN
HEIKKILA, A
PYYKKO, K
ERKKOLA, R
IISALO, E
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 1992, 33 (06) : 629 - 633
[45] Pharmacokinetics of indomethacin in pregnant women with preterm labor
Wang, Xin
Rytting, Erik
Nanovskaya, Tatiana
Patrikeeva, Svetlana
Clark, Shannon
Jasek, Marlo
Hankins, Gary D. V.
Ahmed, Mahmoud S.
Venkataramanan, Raman
Caritis, Steve
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 2011, 204 : S83 - S83
[46] PHARMACOKINETICS OF PIVMECILLINAM HYDROCHLORIDE IN PREGNANT AND NONPREGNANT WOMEN
KJER, JJ
OTTESEN, B
ACTA PHARMACOLOGICA ET TOXICOLOGICA, 1986, 59 (05): : 430 - 431
[47] Pharmacokinetics of oseltamivir among pregnant and nonpregnant women
Beigi, Richard H.
Han, Kelong
Venkataramanan, Raman
Hankins, Gary D.
Clark, Shannon
Hebert, Mary F.
Easterling, Thomas
Zajicek, Anne
Ren, Zhaoxia
Mattison, Donald R.
Caritis, Steve N.
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 2011, 204 (06) : S84 - S88
[48] Pharmacokinetics of Clindamycin in Pregnant Women in the Peripartum Period
Muller, Anouk E.
Mouton, Johan W.
Oostvogel, Paul M.
Dorr, P. Joep
Voskuyl, Rob A.
DeJongh, Joost
Steegers, Eric A. P.
Danhof, Meindert
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2010, 54 (05) : 2175 - 2181
[49] Population Pharmacokinetics of Tenofovir in HIV-1-Infected Pregnant Women and Their Neonates (ANRS 12109)
Hirt, D.
Urien, S.
Ekouevi, D. K.
Rey, E.
Arrive, E.
Blanche, S.
Amani-Bosse, C.
Nerrienet, E.
Gray, G.
Kone, M.
Leang, S. K.
McIntyre, J.
Dabis, F.
Treluyer, J-M
CLINICAL PHARMACOLOGY & THERAPEUTICS, 2009, 85 (02) : 182 - 189
[50] Population Pharmacokinetics of Lumefantrine in Pregnant Women Treated with Artemether-Lumefantrine for Uncomplicated Plasmodium falciparum Malaria
Tarning, Joel
McGready, Rose
Lindegardh, Niklas
Ashley, Elizabeth A.
Pimanpanarak, Mupawjay
Kamanikom, Benjamas
Annerberg, Anna
Day, Nicholas P. J.
Stepniewska, Kasia
Singhasivanon, Pratap
White, Nicholas J.
Nosten, Francois
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2009, 53 (09) : 3837 - 3846

← 1 2 3 4 5 →