Factors affecting the degree of completeness of skin regeneration in mammals

In the majority of experimental studies on skin regeneration, which were conducted on the backs of rats and mice, wound healing resulted in the formation of epithelized scars of the connective tissue. Using various methods to influence the process of skin regeneration in this and other models, we were able to obtain in some cases the organotypic regeneration accompanied by the formation of skin derivatives. We conclude that we have detected factors affecting the extent of posttraumatic skin regeneration in mammals.