Synthesis of the FR900482 tetracyclic ring system by oxidation of a 2,3-dihydro-1H-pyrrolo[1,2-a]indole derivative

被引：18
|
作者：
Zhang, WH [1 ]
Wang, C [1 ]
Jimenez, LS [1 ]
机构：
[1] Rutgers State Univ, Dept Chem, Piscataway, NJ 08854 USA
来源：
SYNTHETIC COMMUNICATIONS | 2000年 / 30卷 / 02期
基金：
美国国家科学基金会;
关键词：
D O I：
10.1080/00397910008087328
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The tetracyclic FR900482 ring skeleton has been synthesized from the 2,3-dihydro-1H-pyrrolo[1,2-a]indole derivative 5. Treatment of 5 with osmium tetraoxide, hydrogen sulfide, magnesium monoperoxyphthalic acid (MMPP), and triphenylphosphine resulted in the formation of 12.
引用
收藏
页码：351 / 366
页数：16
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