Synthesis of 5-aryl-2-[spiro-(1,3-dithiolane)-2,4'-(3'-chloro-2'-azetidinon)-1'-yl]-1,3,4-oxa (thia)diazoles and 5-aryl-2-[spiro-(1,3-dithiolane)-2,2'-(4'-thiazolidinon)-3'-yl]-1,3,4-oxa(thia)diazoles as antimicrobial agents

5-Aryl-2-[spiro-(1,3-dithiolane)-2,4'-(3'-chloro-2'-azetidinon)-1'-yl]-1,3,4-oxa(thia)diazoles 4 and 5- aryl-2-[spiro-(1,3-dithiolane)-2,2'-(4'-thiazolidinon)- 3'-yl]- 1,3,4-oxa (thia)-diazoles 5 have been synthesised from 5-aryl-2-(1,3-dithiolan-2-yl)imino-1,3,4-oxa(thia) diazoles 3 with chloro acetyl chloride and mercapto acetic acid, respectively. These compounds have been screened on Aspergillus niger, Pyricularia oryzae, Fusarium oxysporum and Cephalosporum sacchari; and Escherichia coli, Solmonella typhi and Bacillus aureus for their antifungal and antibacterial activities, respectively.