High-dose chemotherapy with autologous peripheral blood stem cell transplantation for metastatic gastric leiomyosarcoma

被引：9
|
作者：
Fetscher, S [1 ]
Brugger, W [1 ]
Bertz, H [1 ]
Krieger, G [1 ]
Kanz, L [1 ]
Mertelsmann, R [1 ]
Lange, W [1 ]
机构：
[1] UNIV TUBINGEN,MED CTR,DEPT INTERNAL MED,DIV HEMATOL & ONCOL,TUBINGEN,GERMANY
来源：
BONE MARROW TRANSPLANTATION | 1997年 / 20卷 / 09期
关键词：
gastrointestinal sarcoma; leiomyosarcoma; soft tissue sarcoma; high-dose chemotherapy; autologous peripheral blood stem cell transplantation;
D O I：
10.1038/sj.bmt.1700970
中图分类号：
Q6 [生物物理学];
学科分类号：
071011 ;
摘要：
We report a case of metastatic gastrointestinal leiomyosarcoma treated with high-dose combination chemotherapy and autologous peripheral blood stem cell transplantation. After incomplete surgical resection, enteral, peritoneal and hepatic involvement remained, Postoperatively, standard-dose chemotherapy with etoposide, ifosfamide, cisplatin and epirubicin, and high-dose chemotherapy with the same agents (carboplatin replacing cisplatin) was given, Treatment was well tolerated and the patient remains in complete remission at 36+ months, We conclude that high-dose chemotherapy followed by autologous peripheral blood stem cell transplantation may be of use as treatment for inoperable residual disease after resection of the primary lesion in gastrointestinal and other soft tissue sarcomas.
引用
收藏
页码：787 / 788
页数：2
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