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- [41] BRCA1 and BRCA2 in breast cancerBreast Cancer Research and Treatment, 1999, 54 : 1 - 10Xiaohong Yang论文数: 0 引用数: 0 h-index: 0机构: Georgetown University Medical Center,Lombardi Cancer CenterMarc E. Lippman论文数: 0 引用数: 0 h-index: 0机构: Georgetown University Medical Center,Lombardi Cancer Center
- [42] Are Endometrial Cancers Arising in BRCA1/BRCA2 Germline Mutations Carriers True BRCA1/BRCA2 Cancers?MODERN PATHOLOGY, 2019, 32Paula, Arnaud Da Cruz论文数: 0 引用数: 0 h-index: 0机构: Mem Sloan Kettering Canc Ctr, 1275 York Ave, New York, NY 10021 USA Mem Sloan Kettering Canc Ctr, 1275 York Ave, New York, NY 10021 USASmith, Evan论文数: 0 引用数: 0 h-index: 0机构: Mem Sloan Kettering Canc Ctr, 1275 York Ave, New York, NY 10021 USA Mem Sloan Kettering Canc Ctr, 1275 York Ave, New York, NY 10021 USACadoo, Karen论文数: 0 引用数: 0 h-index: 0机构: Mem Sloan Kettering Canc Ctr, 1275 York Ave, New York, NY 10021 USA Mem Sloan Kettering Canc Ctr, 1275 York Ave, New York, NY 10021 USAAbu-Rustum, Nadeem论文数: 0 引用数: 0 h-index: 0机构: Mem Sloan Kettering Canc Ctr, 1275 York Ave, New York, NY 10021 USA Mem Sloan Kettering Canc Ctr, 1275 York Ave, New York, NY 10021 USAPei, Xin论文数: 0 引用数: 0 h-index: 0机构: Mem Sloan Kettering Canc Ctr, 1275 York Ave, New York, NY 10021 USA Mem Sloan Kettering Canc Ctr, 1275 York Ave, New York, NY 10021 USARiaz, Nadeem论文数: 0 引用数: 0 h-index: 0机构: Mem Sloan Kettering Canc Ctr, 1275 York Ave, New York, NY 10021 USA Mem Sloan Kettering Canc Ctr, 1275 York Ave, New York, NY 10021 USARobson, Mark论文数: 0 引用数: 0 h-index: 0机构: Mem Sloan Kettering Canc Ctr, 1275 York Ave, New York, NY 10021 USA Mem Sloan Kettering Canc Ctr, 1275 York Ave, New York, NY 10021 USAReis-Filho, Jorge论文数: 0 引用数: 0 h-index: 0机构: Mem Sloan Kettering Canc Ctr, 1275 York Ave, New York, NY 10021 USA Mem Sloan Kettering Canc Ctr, 1275 York Ave, New York, NY 10021 USAMandelker, Diana论文数: 0 引用数: 0 h-index: 0机构: Mem Sloan Kettering Canc Ctr, 1275 York Ave, New York, NY 10021 USA Mem Sloan Kettering Canc Ctr, 1275 York Ave, New York, NY 10021 USAWeigelt, Britta论文数: 0 引用数: 0 h-index: 0机构: Mem Sloan Kettering Canc Ctr, 1275 York Ave, New York, NY 10021 USA Mem Sloan Kettering Canc Ctr, 1275 York Ave, New York, NY 10021 USA
- [43] Are Endometrial Cancers Arising in BRCA1/BRCA2 Germline Mutations Carriers True BRCA1/BRCA2 Cancers?LABORATORY INVESTIGATION, 2019, 99Paula, Arnaud Da Cruz论文数: 0 引用数: 0 h-index: 0机构: Mem Sloan Kettering Canc Ctr, 1275 York Ave, New York, NY 10021 USA Mem Sloan Kettering Canc Ctr, 1275 York Ave, New York, NY 10021 USASmith, Evan论文数: 0 引用数: 0 h-index: 0机构: Mem Sloan Kettering Canc Ctr, 1275 York Ave, New York, NY 10021 USA Mem Sloan Kettering Canc Ctr, 1275 York Ave, New York, NY 10021 USACadoo, Karen论文数: 0 引用数: 0 h-index: 0机构: Mem Sloan Kettering Canc Ctr, 1275 York Ave, New York, NY 10021 USA Mem Sloan Kettering Canc Ctr, 1275 York Ave, New York, NY 10021 USAAbu-Rustum, Nadeem论文数: 0 引用数: 0 h-index: 0机构: Mem Sloan Kettering Canc Ctr, 1275 York Ave, New York, NY 10021 USA Mem Sloan Kettering Canc Ctr, 1275 York Ave, New York, NY 10021 USAPei, Xin论文数: 0 引用数: 0 h-index: 0机构: Mem Sloan Kettering Canc Ctr, 1275 York Ave, New York, NY 10021 USA Mem Sloan Kettering Canc Ctr, 1275 York Ave, New York, NY 10021 USARiaz, Nadeem论文数: 0 引用数: 0 h-index: 0机构: Mem Sloan Kettering Canc Ctr, 1275 York Ave, New York, NY 10021 USA Mem Sloan Kettering Canc Ctr, 1275 York Ave, New York, NY 10021 USARobson, Mark论文数: 0 引用数: 0 h-index: 0机构: Mem Sloan Kettering Canc Ctr, 1275 York Ave, New York, NY 10021 USA Mem Sloan Kettering Canc Ctr, 1275 York Ave, New York, NY 10021 USAReis-Filho, Jorge论文数: 0 引用数: 0 h-index: 0机构: Mem Sloan Kettering Canc Ctr, 1275 York Ave, New York, NY 10021 USA Mem Sloan Kettering Canc Ctr, 1275 York Ave, New York, NY 10021 USAMandelker, Diana论文数: 0 引用数: 0 h-index: 0机构: Mem Sloan Kettering Canc Ctr, 1275 York Ave, New York, NY 10021 USA Mem Sloan Kettering Canc Ctr, 1275 York Ave, New York, NY 10021 USAWeigelt, Britta论文数: 0 引用数: 0 h-index: 0机构: Mem Sloan Kettering Canc Ctr, 1275 York Ave, New York, NY 10021 USA Mem Sloan Kettering Canc Ctr, 1275 York Ave, New York, NY 10021 USA
- [44] Pedigree analysis equally identifies cases of pancreatic cancer in families with BRCA1 and BRCA2 mutationsCANCER RESEARCH, 2018, 78 (13)Schrock, Evelin论文数: 0 引用数: 0 h-index: 0机构: Tech Univ Dresden, Med Fak Carl Gustav Carus, Inst Klin Genet, Dresden, Germany Tech Univ Dresden, Med Fak Carl Gustav Carus, Inst Klin Genet, Dresden, GermanyHackmann, Karl论文数: 0 引用数: 0 h-index: 0机构: Tech Univ Dresden, Med Fak Carl Gustav Carus, Inst Klin Genet, Dresden, Germany Tech Univ Dresden, Med Fak Carl Gustav Carus, Inst Klin Genet, Dresden, GermanyKuhlee, Franziska论文数: 0 引用数: 0 h-index: 0机构: Tech Univ Dresden, Med Fak Carl Gustav Carus, Inst Klin Genet, Dresden, Germany Tech Univ Dresden, Med Fak Carl Gustav Carus, Inst Klin Genet, Dresden, Germany论文数: 引用数: h-index:机构:Wagner, Johannes论文数: 0 引用数: 0 h-index: 0机构: Tech Univ Dresden, Med Fak Carl Gustav Carus, Inst Klin Genet, Dresden, Germany Tech Univ Dresden, Med Fak Carl Gustav Carus, Inst Klin Genet, Dresden, GermanyKahlert, Anne-Karin论文数: 0 引用数: 0 h-index: 0机构: Tech Univ Dresden, Med Fak Carl Gustav Carus, Inst Klin Genet, Dresden, Germany Tech Univ Dresden, Med Fak Carl Gustav Carus, Inst Klin Genet, Dresden, GermanyPorrmann, Joseph论文数: 0 引用数: 0 h-index: 0机构: Tech Univ Dresden, Med Fak Carl Gustav Carus, Inst Klin Genet, Dresden, Germany Tech Univ Dresden, Med Fak Carl Gustav Carus, Inst Klin Genet, Dresden, Germany论文数: 引用数: h-index:机构:论文数: 引用数: h-index:机构:Baretton, Gustavo论文数: 0 引用数: 0 h-index: 0机构: Tech Univ Dresden, Univ Klinikum Carl Gustav Carus, Inst Pathol, Dresden, Germany Tech Univ Dresden, Med Fak Carl Gustav Carus, Inst Klin Genet, Dresden, GermanyKast, Karin论文数: 0 引用数: 0 h-index: 0机构: Tech Univ Dresden, Univ Klinikum Carl Gustav Carus, Klin & Poliklin Frauenheilkunde & Geburtshilfe, Dresden, Germany Tech Univ Dresden, Med Fak Carl Gustav Carus, Inst Klin Genet, Dresden, GermanyWimberger, Pauline论文数: 0 引用数: 0 h-index: 0机构: Tech Univ Dresden, Univ Klinikum Carl Gustav Carus, Klin & Poliklin Frauenheilkunde & Geburtshilfe, Dresden, Germany Tech Univ Dresden, Med Fak Carl Gustav Carus, Inst Klin Genet, Dresden, GermanyLaniado, Michael论文数: 0 引用数: 0 h-index: 0机构: Tech Univ Dresden, Univ Klinikum Carl Gustav Carus, Klin & Poliklin Nukl Med, Dresden, Germany Tech Univ Dresden, Med Fak Carl Gustav Carus, Inst Klin Genet, Dresden, GermanyKahlert, Christoph论文数: 0 引用数: 0 h-index: 0机构: Tech Univ Dresden, Univ Klinikum Carl Gustav Carus, Klin & Poliklin Viszeral Thorax & Gefasschirurg, Dresden, Germany Tech Univ Dresden, Med Fak Carl Gustav Carus, Inst Klin Genet, Dresden, GermanyWelsch, Thilo论文数: 0 引用数: 0 h-index: 0机构: Tech Univ Dresden, Univ Klinikum Carl Gustav Carus, Klin & Poliklin Viszeral Thorax & Gefasschirurg, Dresden, Germany Tech Univ Dresden, Med Fak Carl Gustav Carus, Inst Klin Genet, Dresden, GermanyWeitz, Juergen论文数: 0 引用数: 0 h-index: 0机构: Tech Univ Dresden, Univ Klinikum Carl Gustav Carus, Klin & Poliklin Viszeral Thorax & Gefasschirurg, Dresden, Germany Tech Univ Dresden, Med Fak Carl Gustav Carus, Inst Klin Genet, Dresden, GermanyKlink, Barbara论文数: 0 引用数: 0 h-index: 0机构: Tech Univ Dresden, Med Fak Carl Gustav Carus, Inst Klin Genet, Dresden, Germany Tech Univ Dresden, Med Fak Carl Gustav Carus, Inst Klin Genet, Dresden, Germany论文数: 引用数: h-index:机构:论文数: 引用数: h-index:机构:
- [45] BRCA1 and BRCA2 mutations sensitize to chemotherapy in patient-derived pancreatic cancer xenograftsBRITISH JOURNAL OF CANCER, 2015, 113 (03) : 425 - 432Lohse, I.论文数: 0 引用数: 0 h-index: 0机构: Univ Hlth Network, Princess Margaret Canc Ctr, Ontario Canc Inst, Toronto, ON M5G 2M9, Canada Univ Hlth Network, Princess Margaret Canc Ctr, Campbell Family Canc Res Inst, Toronto, ON M5G 2M9, Canada Univ Hlth Network, Princess Margaret Canc Ctr, Ontario Canc Inst, Toronto, ON M5G 2M9, CanadaBorgida, A.论文数: 0 引用数: 0 h-index: 0机构: Mt Sinai Hosp, Joseph & Wolf Lebov Hlth Complex, Toronto, ON M5G 1X5, Canada Univ Hlth Network, Princess Margaret Canc Ctr, Ontario Canc Inst, Toronto, ON M5G 2M9, CanadaCao, P.论文数: 0 引用数: 0 h-index: 0机构: Univ Hlth Network, Princess Margaret Canc Ctr, Ontario Canc Inst, Toronto, ON M5G 2M9, Canada Univ Hlth Network, Princess Margaret Canc Ctr, Campbell Family Canc Res Inst, Toronto, ON M5G 2M9, Canada Univ Hlth Network, Princess Margaret Canc Ctr, Ontario Canc Inst, Toronto, ON M5G 2M9, CanadaCheung, M.论文数: 0 引用数: 0 h-index: 0机构: Univ Hlth Network, Princess Margaret Canc Ctr, Ontario Canc Inst, Toronto, ON M5G 2M9, Canada Univ Hlth Network, Princess Margaret Canc Ctr, Campbell Family Canc Res Inst, Toronto, ON M5G 2M9, Canada Univ Hlth Network, Princess Margaret Canc Ctr, Ontario Canc Inst, Toronto, ON M5G 2M9, CanadaPintilie, M.论文数: 0 引用数: 0 h-index: 0机构: Univ Hlth Network, Princess Margaret Canc Ctr, Ontario Canc Inst, Toronto, ON M5G 2M9, Canada Univ Hlth Network, Princess Margaret Canc Ctr, Campbell Family Canc Res Inst, Toronto, ON M5G 2M9, Canada Univ Hlth Network, Princess Margaret Canc Ctr, Ontario Canc Inst, Toronto, ON M5G 2M9, CanadaBianco, T.论文数: 0 引用数: 0 h-index: 0机构: Mt Sinai Hosp, Joseph & Wolf Lebov Hlth Complex, Toronto, ON M5G 1X5, Canada Ontario Inst Canc Res, Translat Res Initiat Pancreas Canc, Toronto, ON M5G 2M9, Canada Univ Hlth Network, Princess Margaret Canc Ctr, Ontario Canc Inst, Toronto, ON M5G 2M9, CanadaHolter, S.论文数: 0 引用数: 0 h-index: 0机构: Mt Sinai Hosp, Joseph & Wolf Lebov Hlth Complex, Toronto, ON M5G 1X5, Canada Univ Hlth Network, Princess Margaret Canc Ctr, Ontario Canc Inst, Toronto, ON M5G 2M9, CanadaIbrahimov, E.论文数: 0 引用数: 0 h-index: 0机构: Univ Hlth Network, Princess Margaret Canc Ctr, Ontario Canc Inst, Toronto, ON M5G 2M9, Canada Univ Hlth Network, Princess Margaret Canc Ctr, Campbell Family Canc Res Inst, Toronto, ON M5G 2M9, Canada Mt Sinai Hosp, Joseph & Wolf Lebov Hlth Complex, Toronto, ON M5G 1X5, Canada Univ Hlth Network, Princess Margaret Canc Ctr, Ontario Canc Inst, Toronto, ON M5G 2M9, CanadaKumareswaran, R.论文数: 0 引用数: 0 h-index: 0机构: Univ Hlth Network, Princess Margaret Canc Ctr, Ontario Canc Inst, Toronto, ON M5G 2M9, Canada Univ Hlth Network, Princess Margaret Canc Ctr, Campbell Family Canc Res Inst, Toronto, ON M5G 2M9, Canada Univ Hlth Network, Princess Margaret Canc Ctr, Ontario Canc Inst, Toronto, ON M5G 2M9, CanadaBristow, R. G.论文数: 0 引用数: 0 h-index: 0机构: Univ Hlth Network, Princess Margaret Canc Ctr, Ontario Canc Inst, Toronto, ON M5G 2M9, Canada Univ Hlth Network, Princess Margaret Canc Ctr, Campbell Family Canc Res Inst, Toronto, ON M5G 2M9, Canada Univ Hlth Network, Princess Margaret Canc Ctr, Ontario Canc Inst, Toronto, ON M5G 2M9, CanadaTsao, M-S论文数: 0 引用数: 0 h-index: 0机构: Univ Hlth Network, Princess Margaret Canc Ctr, Ontario Canc Inst, Toronto, ON M5G 2M9, Canada Univ Hlth Network, Princess Margaret Canc Ctr, Campbell Family Canc Res Inst, Toronto, ON M5G 2M9, Canada Univ Hlth Network, Dept Pathol, Toronto, ON M5G 2M9, Canada Univ Toronto, Dept Lab Med & Pathol, Toronto, ON M5G 2M9, Canada Univ Hlth Network, Princess Margaret Canc Ctr, Ontario Canc Inst, Toronto, ON M5G 2M9, CanadaGallinger, S.论文数: 0 引用数: 0 h-index: 0机构: Mt Sinai Hosp, Joseph & Wolf Lebov Hlth Complex, Toronto, ON M5G 1X5, Canada Ontario Inst Canc Res, Translat Res Initiat Pancreas Canc, Toronto, ON M5G 2M9, Canada Univ Hlth Network, Princess Margaret Canc Ctr, Ontario Canc Inst, Toronto, ON M5G 2M9, CanadaHedley, D. W.论文数: 0 引用数: 0 h-index: 0机构: Univ Hlth Network, Princess Margaret Canc Ctr, Ontario Canc Inst, Toronto, ON M5G 2M9, Canada Univ Hlth Network, Princess Margaret Canc Ctr, Campbell Family Canc Res Inst, Toronto, ON M5G 2M9, Canada Ontario Inst Canc Res, Translat Res Initiat Pancreas Canc, Toronto, ON M5G 2M9, Canada Princess Margaret Canc Ctr, Dept Med Oncol & Haematol, Toronto, ON M5G 2M9, Canada Univ Hlth Network, Princess Margaret Canc Ctr, Ontario Canc Inst, Toronto, ON M5G 2M9, Canada
- [46] BRCA1 and BRCA2 mutations sensitize to chemotherapy in patient-derived pancreatic cancer xenograftsBritish Journal of Cancer, 2015, 113 : 425 - 432I Lohse论文数: 0 引用数: 0 h-index: 0机构: Ontario Cancer Institute and Campbell Family Cancer Research Institute,Department of PathologyA Borgida论文数: 0 引用数: 0 h-index: 0机构: Ontario Cancer Institute and Campbell Family Cancer Research Institute,Department of PathologyP Cao论文数: 0 引用数: 0 h-index: 0机构: Ontario Cancer Institute and Campbell Family Cancer Research Institute,Department of PathologyM Cheung论文数: 0 引用数: 0 h-index: 0机构: Ontario Cancer Institute and Campbell Family Cancer Research Institute,Department of PathologyM Pintilie论文数: 0 引用数: 0 h-index: 0机构: Ontario Cancer Institute and Campbell Family Cancer Research Institute,Department of PathologyT Bianco论文数: 0 引用数: 0 h-index: 0机构: Ontario Cancer Institute and Campbell Family Cancer Research Institute,Department of PathologyS Holter论文数: 0 引用数: 0 h-index: 0机构: Ontario Cancer Institute and Campbell Family Cancer Research Institute,Department of PathologyE Ibrahimov论文数: 0 引用数: 0 h-index: 0机构: Ontario Cancer Institute and Campbell Family Cancer Research Institute,Department of PathologyR Kumareswaran论文数: 0 引用数: 0 h-index: 0机构: Ontario Cancer Institute and Campbell Family Cancer Research Institute,Department of PathologyR G Bristow论文数: 0 引用数: 0 h-index: 0机构: Ontario Cancer Institute and Campbell Family Cancer Research Institute,Department of PathologyM-S Tsao论文数: 0 引用数: 0 h-index: 0机构: Ontario Cancer Institute and Campbell Family Cancer Research Institute,Department of PathologyS Gallinger论文数: 0 引用数: 0 h-index: 0机构: Ontario Cancer Institute and Campbell Family Cancer Research Institute,Department of PathologyD W Hedley论文数: 0 引用数: 0 h-index: 0机构: Ontario Cancer Institute and Campbell Family Cancer Research Institute,Department of Pathology
- [47] BRCA1 and BRCA2CURRENT BIOLOGY, 2000, 10 (16) : R582 - R582Bertwistle, D论文数: 0 引用数: 0 h-index: 0机构: Inst Canc Res, Chester Beatty Labs, Breakthrough Breast Canc Res Ctr, London SW3 6JB, England Inst Canc Res, Chester Beatty Labs, Breakthrough Breast Canc Res Ctr, London SW3 6JB, EnglandAshworth, A论文数: 0 引用数: 0 h-index: 0机构: Inst Canc Res, Chester Beatty Labs, Breakthrough Breast Canc Res Ctr, London SW3 6JB, England Inst Canc Res, Chester Beatty Labs, Breakthrough Breast Canc Res Ctr, London SW3 6JB, England
- [48] Distribution of BRCA1 and BRCA2 Mutations in Asian Patients with Breast CancerJOURNAL OF BREAST CANCER, 2013, 16 (04) : 357 - 365Kim, Haeyoung论文数: 0 引用数: 0 h-index: 0机构: Hallym Univ, Dongtan Sacred Heart Hosp, Dept Radiat Oncol, Hwaseong, South Korea Hallym Univ, Dongtan Sacred Heart Hosp, Dept Radiat Oncol, Hwaseong, South KoreaChoi, Doo Ho论文数: 0 引用数: 0 h-index: 0机构: Sungkyunkwan Univ, Sch Med, Samsung Med Ctr, Dept Radiat Oncol, Seoul 135710, South Korea Hallym Univ, Dongtan Sacred Heart Hosp, Dept Radiat Oncol, Hwaseong, South Korea
- [49] High incidence of mutations in BRCA1 and BRCA2 genes in ovarian cancerBULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE, 2007, 144 (01) : 83 - 85Smirnova, T. Yu.论文数: 0 引用数: 0 h-index: 0机构: Russian Acad Med Sci, Med Genet Res Ctr, Moscow 109801, RussiaPospekhova, N. I.论文数: 0 引用数: 0 h-index: 0机构: Russian Acad Med Sci, Med Genet Res Ctr, Moscow 109801, RussiaLyubchenko, L. N.论文数: 0 引用数: 0 h-index: 0机构: Russian Acad Med Sci, Med Genet Res Ctr, Moscow 109801, RussiaTjulandin, S. A.论文数: 0 引用数: 0 h-index: 0机构: Russian Acad Med Sci, Med Genet Res Ctr, Moscow 109801, RussiaGar'kavtseva, R. F.论文数: 0 引用数: 0 h-index: 0机构: Russian Acad Med Sci, Med Genet Res Ctr, Moscow 109801, RussiaGinter, E. K.论文数: 0 引用数: 0 h-index: 0机构: Russian Acad Med Sci, Med Genet Res Ctr, Moscow 109801, RussiaKarpukhin, A. V.论文数: 0 引用数: 0 h-index: 0机构: Russian Acad Med Sci, Med Genet Res Ctr, Moscow 109801, Russia Russian Acad Med Sci, Med Genet Res Ctr, Moscow 109801, Russia
- [50] Prevalence of BRCA1 and BRCA2 mutations in triple negative breast cancerJOURNAL OF MEDICAL GENETICS, 2011, 48 (08) : 520 - 522Evans, D. G.论文数: 0 引用数: 0 h-index: 0机构: Univ Hosp S Manchester NHS Trust, Genesis Prevent Ctr, Manchester, Lancs, England Univ Manchester, Manchester Acad Hlth Sci Ctr, Cent Manchester Fdn Trust, St Marys Hosp, Manchester M13 9WL, Lancs, England Univ Hosp S Manchester NHS Trust, Genesis Prevent Ctr, Manchester, Lancs, EnglandHowell, A.论文数: 0 引用数: 0 h-index: 0机构: Univ Hosp S Manchester NHS Trust, Genesis Prevent Ctr, Manchester, Lancs, England Christie NHS Trust, CR UK Dept Med Oncol, Manchester, Lancs, England Univ Hosp S Manchester NHS Trust, Genesis Prevent Ctr, Manchester, Lancs, EnglandWard, D.论文数: 0 引用数: 0 h-index: 0机构: Salisbury Dist Hosp, Wessex Reg Genet Lab, Salisbury NHS Fdn Trust, Salisbury, Wilts, England Univ Hosp S Manchester NHS Trust, Genesis Prevent Ctr, Manchester, Lancs, EnglandLalloo, F.论文数: 0 引用数: 0 h-index: 0机构: Univ Manchester, Manchester Acad Hlth Sci Ctr, Cent Manchester Fdn Trust, St Marys Hosp, Manchester M13 9WL, Lancs, England Univ Hosp S Manchester NHS Trust, Genesis Prevent Ctr, Manchester, Lancs, EnglandJones, J. L.论文数: 0 引用数: 0 h-index: 0机构: Barts & Univ London, Sch Med & Dent, John Vane Sci Ctr, Tumour Biol Dept, London, England Univ Hosp S Manchester NHS Trust, Genesis Prevent Ctr, Manchester, Lancs, EnglandEccles, D. M.论文数: 0 引用数: 0 h-index: 0机构: Univ Southampton, Fac Med, Southampton Univ Hosp Trust, Southampton SO9 5NH, Hants, England Univ Hosp S Manchester NHS Trust, Genesis Prevent Ctr, Manchester, Lancs, England