AgF-Mediated Dialkylation of Activate Alkenes: An Efficient Access to Nitrile-Containing Spirooxindoles

被引：12
|
作者：
Wu, Liang [1 ]
Chen, Pinhong [1 ]
Liu, Guosheng [1 ]
机构：
[1] Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Organometall Chem, Shanghai 200032, Peoples R China
来源：
CHINESE JOURNAL OF CHEMISTRY | 2014年 / 32卷 / 08期
关键词：
spirooxindoles; activated alkenes; silver fluoride; acetonitrile; C-H bond cleavage; CATALYZED OXIDATIVE ARYLALKYLATION; ENANTIOSELECTIVE SYNTHESIS; BOND-CLEAVAGE; C-H; AMINOFLUORINATION; FLUORINATION;
D O I：
10.1002/cjoc.201400350
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A novel Ag-mediated dialkylation reaction of alkenes was disclosed, in which AgF was essential to activate C-H bond of acetonitrile. This reaction provided an efficient way to nitrile-containing spirooxindoles from readily available (1H-indol-3-yl)methanamine derivatives.
引用
收藏
页码：681 / 684
页数：4
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