Use of umbilical cord and cord blood-derived stem cells for tissue repair and regeneration

被引：16

作者：

Biazar, Esmaeil ^{[1
]}

机构：

[1] Islamic Azad Univ, Tonekabon Branch, Dept Biomed Engn, Tonekabon, Iran

来源：

EXPERT OPINION ON BIOLOGICAL THERAPY | 2014年 / 14卷 / 03期

关键词：

in vivo; stem cells; tissue repair and regeneration; umbilical cord; ACUTE MYOCARDIAL-INFARCTION; ENDOTHELIAL PROGENITOR CELLS; IMPROVE CARDIAC-FUNCTION; THICKNESS SKIN DEFECTS; BONE-MARROW; MOUSE MODEL; RAT MODEL; IN-VIVO; PHENOTYPIC CHARACTERIZATION; MONONUCLEAR-CELLS;

D O I：

10.1517/14712598.2014.867943

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Introduction: Potential use of umbilical cord (UC) is one of the most exciting frontiers in medicine for repairing damaged tissues. UC and cord blood-derived stem cells are the world's largest potential sources of stem cells. UC contains a mixture of stem and progenitor cells at different lineage commitment stages and UC has been verified as a candidate for cell-based therapies and tissue engineering applications due to the capability of these cells for extensive self-renewal and multi-lineage character in differentiation potential. Areas covered: UC-based repair or regeneration of organs (i.e., heart, nerve, skin, etc.) is a high-priority research worldwide. Expert opinion: The aim of this review is to summarize the knowledge about UC with main focus on its applications for tissue repair and regeneration.

引用

页码：301 / 310

页数：10

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