A phase III randomized trial of chemoimmunotherapy comprising gemcitabine and capecitabine with or without telomerase vaccine GV1001 in patients with locally advanced or metastatic pancreatic cancer.

被引:0
|
作者
Middleton, Gary William
Valle, Juan W.
Wadsley, Jonathan
Propper, David
Coxon, Fareeda Y.
Ross, Paul J.
Madhusudan, Srinivasan
Roques, Tom
Cunningham, David
Corrie, Philippa
Greenhalf, William
Shaw, Victoria
Cox, Trevor F.
Silcocks, Paul
Nanson, Gemma
Neoptolemos, John P.
机构
[1] Univ Birmingham, Birmingham, W Midlands, England
[2] Christie Hosp NHS Fdn Trust, European ENETS Ctr Excellence, Manchester, Lancs, England
[3] Weston Pk Hosp, Dept Clin Oncol, Sheffield, S Yorkshire, England
[4] St Bartholomews Hosp, Inst Canc, Ctr Med Oncol, London, England
[5] Northern Ctr Canc Care, Newcastle Upon Tyne, Tyne & Wear, England
[6] Guys & St Thomas NHS Fdn Trust, London, England
[7] Univ Nottingham Hosp, Sch Mol Med Sci, Nottingham NG7 2UH, England
[8] Norfolk & Norwich Univ Hosp, Norwich, Norfolk, England
[9] Royal Marsden Hosp NHS Fdn Trust, London, England
[10] Addenbrookes Hosp, Ctr Oncol, Cambridge, England
[11] Univ Liverpool, Liverpool L69 3BX, Merseyside, England
关键词
D O I
暂无
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
LBA4004
引用
收藏
页数:1
相关论文
共 50 条
  • [21] Phase II Trial to Evaluate Gemcitabine and Etoposide for Locally Advanced or Metastatic Pancreatic Cancer
    Melnik, Marianne K.
    Webb, Craig P.
    Richardson, Patrick J.
    Luttenton, Charles R.
    Campbell, Alan D.
    Monroe, Thomas J.
    O'Rourke, Timothy J.
    Yost, Kathleen J.
    Szczepanek, Connie M.
    Bassett, Michelle R.
    Truszkowski, Kimberly J.
    Stein, Phyllis
    Van Brocklin, Matthew W.
    Davis, Alan T.
    Bedolla, Gabriela
    Vande Woude, George F.
    Koo, Han-Mo
    MOLECULAR CANCER THERAPEUTICS, 2010, 9 (08) : 2423 - 2429
  • [22] A phase I trial of MTA and gemcitabine in patients with locally advanced or metastatic cancer
    Adjei, AA
    Erlichman, C
    SEMINARS IN ONCOLOGY, 1999, 26 (02) : 94 - 98
  • [23] Gemcitabine in combination with oxaliplatin compared with gemcitabine alone in locally advanced or metastatic pancreatic cancer:: Results of a GERCOR and GISCAD phase III trial
    Louvet, C
    Labianca, R
    Hammel, P
    Lledo, G
    Zampino, MG
    André, T
    Zaniboni, A
    Ducreux, M
    Aitini, E
    Taïeb, J
    Faroux, R
    Lepere, C
    de Gramont, A
    JOURNAL OF CLINICAL ONCOLOGY, 2005, 23 (15) : 3509 - 3516
  • [24] Capecitabine plus oxaliplatin (CapOx) versus capecitabine plus gemcitabine (CapGem) versus gemcitabine plus oxaliplatin (GemOx): A randomized phase II trial in advanced pancreatic cancer.
    Heinemann, V
    Hoehler, T
    Seipelt, G
    Wein, A
    Golf, A
    Mahlberg, R
    Schmid, B
    Boeck, S
    Neugebauer, S
    Hochhaus, A
    Grosshadern, K
    JOURNAL OF CLINICAL ONCOLOGY, 2005, 23 (16) : 315S - 315S
  • [25] Gemcitabine versus mitomycin versus gemcitabine/mitomycin in the treatment of locally advanced and metastatic pancreatic cancer - a randomized multicenter phase II trial
    Block, A.
    Tuinmann, G.
    Boehlke, I
    Mueller, L.
    Lipp, R.
    Porschen, R.
    von Hielmcrone, K.
    Pietsch, M.
    Schulte, F.
    Nissen, S-O
    Pichlmeier, U.
    Hossfeld, D. K.
    Bokemeyer, C.
    ONCOLOGY RESEARCH AND TREATMENT, 2019, 42 : 36 - 37
  • [26] Gemcitabine and oxaliplatin combination: A multicenter phase II trial in unfit patients with locally advanced or metastatic urothelial cancer.
    Font, A
    Esteban, E
    Carles, J
    Climent, MA
    Gonzalez-Larriba, JL
    Berrocal, A
    Bellmunt, J
    Garcia-Ribas, I
    Marfa, X
    Fabregat, X
    JOURNAL OF CLINICAL ONCOLOGY, 2004, 22 (14) : 392S - 392S
  • [27] A phase II randomized, placebo controlled study to evaluate the efficacy of the combination of gemcitabine, erlotinib, and metformin in patients with locally advanced or metastatic pancreatic cancer.
    Wilmink, Johanna
    Kordes, Sil
    Zwinderman, Koos
    Mathot, Ron
    Punt, Cornelis J. A.
    Richel, Dirk
    JOURNAL OF CLINICAL ONCOLOGY, 2014, 32 (15)
  • [28] Phase II trial of combined regional hyperthermia and gemcitabine for locally advanced or metastatic pancreatic cancer
    Ishikawa, Takeshi
    Kokura, Satoshi
    Sakamoto, Naoyuki
    Ando, Takashi
    Imamoto, Eiko
    Hattori, Takeshi
    Oyamada, Hirokazu
    Yoshinami, Naomi
    Sakamoto, Masafumi
    Kitagawa, Kazutomo
    Okumura, Yoko
    Yoshida, Naohisa
    Kamada, Kazuhiro
    Katada, Kazuhiro
    Uchiyama, Kazuhiko
    Handa, Osamu
    Takagi, Tomohisa
    Yasuda, Hiroaki
    Sakagami, Junichi
    Konishi, Hideyuki
    Yagi, Nobuaki
    Naito, Yuji
    Yoshikawa, Toshikazu
    INTERNATIONAL JOURNAL OF HYPERTHERMIA, 2012, 28 (07) : 597 - 604
  • [29] Efficacy of GV1001 with gemcitabine/capecitabine in previously untreated patients with advanced pancreatic ductal adenocarcinoma having high serum eotaxin levels (KG4/2015): an open-label, randomised, Phase 3 trial
    Jung Hyun Jo
    Yong-Tae Kim
    Ho Soon Choi
    Ho Gak Kim
    Hong Sik Lee
    Young Woo Choi
    Dong Uk Kim
    Kwang Hyuck Lee
    Eui Joo Kim
    Joung-Ho Han
    Seung Ok Lee
    Chang-Hwan Park
    Eun Kwang Choi
    Jae Woo Kim
    Jae Yong Cho
    Woo Jin Lee
    Hyungsik Roger Moon
    Mi-Suk Park
    Sangjae Kim
    Si Young Song
    British Journal of Cancer, 2024, 130 : 43 - 52
  • [30] Efficacy of GV1001 with gemcitabine/capecitabine in previously untreated patients with advanced pancreatic ductal adenocarcinoma having high serum eotaxin levels (KG4/2015): an open-label, randomised, Phase 3 trial
    Jo, Jung Hyun
    Kim, Yong-Tae
    Choi, Ho Soon
    Kim, Ho Gak
    Lee, Hong Sik
    Choi, Young Woo
    Kim, Dong Uk
    Lee, Kwang Hyuck
    Kim, Eui Joo
    Han, Joung-Ho
    Lee, Seung Ok
    Park, Chang-Hwan
    Choi, Eun Kwang
    Kim, Jae Woo
    Cho, Jae Yong
    Lee, Woo Jin
    Moon, Hyungsik Roger
    Park, Mi-Suk
    Kim, Sangjae
    Song, Si Young
    BRITISH JOURNAL OF CANCER, 2024, 130 (01) : 43 - 52