An expeditious route to 3 beta,14 beta-dihydroxy-5 beta-androstane-17 beta-carboxaldehyde

被引：5
|
作者：
Gobbini, M
Torri, M
机构：
[1] Prassis Ist. di Ric. Sigma-Tau SpA, 20019 Settimo Milanese (MI)
来源：
SYNTHETIC COMMUNICATIONS | 1997年 / 27卷 / 06期
关键词：
RUTHENIUM TETRAOXIDE; OXIDATION; ALCOHOLS; ACIDS;
D O I：
10.1080/00397919708003058
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
An efficient and practical synthesis of 3 beta, 14 beta-dihydroxy-5 beta-androstane-17 beta-carboxaldehyde is described. The key oxidative cleavage of the unsaturated lactone of 3-acetyldigitoxigenin 1 utilises RuO4 as catalytic and NaIO4 as stoichiometric oxidants.
引用
收藏
页码：1115 / 1122
页数：8
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