1,2,4-Triazine Chemistry Part IV: Synthesis and Chemical Behavior of 3-Functionalized 5,6-Diphenyl-1,2,4-triazines towards Some Nucleophilic and Electrophilic Reagents

被引：23
|
作者：
Abdel-Rahman, Reda M. [1 ]
Makki, Mohamed S. T. [1 ]
Ali, Tarik E. [2 ]
Ibrahim, Magdy A. [2 ]
机构：
[1] King Abdulaziz Univ, Fac Sci, Dept Chem, Jeddah, Saudi Arabia
[2] Ain Shams Univ, Fac Educ, Dept Chem, Cairo, Egypt
来源：
JOURNAL OF HETEROCYCLIC CHEMISTRY | 2015年 / 52卷 / 06期
关键词：
DIELS-ALDER REACTIONS; POTENTIAL ANTI-HIV; UNCONDENSED 1,2,4-TRIAZINES; DERIVATIVES BEARING; RING TRANSFORMATION; ANTICANCER; MOIETY; FLUORINE; SYSTEMS; 3-HYDRAZINO-5,6-DIPHENYL-1,2,4-TRIAZINE;
D O I：
10.1002/jhet.2014
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The synthesis and chemical behavior of 3-functionalized 5,6-diphenyl-1,2,4-triazines towards some electrophilic and nucleophilic reagents are reviewed. The synthesis, unique features, and medicinal, pharmacological, and biological significance of these constituents are also reported.
引用
收藏
页码：1595 / 1607
页数：13
相关论文
共 50 条
  • [41] Synthesis and structural charaterization of a Cu(II) complex with 3-(2-pyridyl)-5,6-diphenyl-1,2,4-triazine (PDPT)
    Soudi, AA
    Marandi, F
    Morsali, A
    Kempe, R
    Hertle, I
    JOURNAL OF COORDINATION CHEMISTRY, 2005, 58 (17) : 1631 - 1637
  • [42] SYNTHESIS OF 1,2,4-TRIAZINES .3. SYNTHESIS OF 1,2,4-TRIAZINE-4-OXIDES
    NEUNHOEFFER, H
    WEISCHED.F
    BOHNISCH, V
    ANNALEN DER CHEMIE-JUSTUS LIEBIG, 1971, 750 (AUG): : 12 - +
  • [43] DERIVATIVES OF 1,2,4-TRIAZINE .1. 3-CHLORO-4-ALKOXYPHENYLACETAMIDRAZONES AND THEIR CONVERSION INTO 1,2,4-TRIAZINES
    AKOPYAN, PR
    OVSEPYAN, TR
    AROYAN, AA
    ARMYANSKII KHIMICHESKII ZHURNAL, 1975, 28 (08): : 641 - 646
  • [44] Transformations of 1,2,4-triazines in reactions with nucleophiles: IV. Nucleophilic substitution of hydrogen in 1,2,4-triazine 4-oxides under acylation conditions
    Rusinov, VL
    Kozhevnikov, DN
    Kovalev, IS
    Chupakhin, ON
    Aleksandrov, GG
    RUSSIAN JOURNAL OF ORGANIC CHEMISTRY, 2000, 36 (07) : 1050 - 1060
  • [45] Energetic 1,2,4-Triazines: 3,5-Diamino-6-nitro-1,2,4-triazine and Its Oxide
    Creegan, Shannon E.
    Zeller, Matthias
    Byrd, Edward F. C.
    Piercey, Davin G.
    CRYSTAL GROWTH & DESIGN, 2021, 21 (07) : 3922 - 3927
  • [46] 1,2,4-TRIAZINES .3. HALOGEN-SULFUR EXCHANGE IN THE PREPARATION OF 5,6-DISUBSTITUTED-1,2,4-TRIAZINES
    NEUMANN, RE
    LOVELETTE, CA
    JOURNAL OF HETEROCYCLIC CHEMISTRY, 1980, 17 (04) : 823 - 824
  • [47] 1,2,4-triazine(VI): Synthesis of 6-ethynyl-1,2,4-triazines from 6-bromo-1,2,4-triazines through Pd-catalyzed coupling reaction
    Lee, JK
    Jung, IR
    Kim, KA
    Chang, SJ
    BULLETIN OF THE KOREAN CHEMICAL SOCIETY, 1996, 17 (11) : 1079 - 1082
  • [48] REACTIONS OF 3-HYDRAZINO-5,6-DIPHENYL-1,2,4-TRIAZINE WITH ALPHA,BETA-BIFUNCTIONAL COMPOUNDS
    ZAHER, HA
    ABDELRAHMAN, RM
    ABDELHALIM, AM
    INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY, 1987, 26 (02): : 110 - 115
  • [49] CHEMISTRY OF 1,2,4-TRIAZINES Ⅱ. AN ANOMALOUS TOSYLATION REACTION OF 3-METHYLMERCAPTO-5-HYDROXY-6-METHYL-1, 2, 4-TRIAZINE
    李鈞
    张礼和
    董振环
    倪沛洲
    王序
    Science China Mathematics, 1964, (02) : 231 - 239
  • [50] From 3-chloromethyl-1,2,4-triazine 4-oxides to various substituted pyridines and 1,2,4-triazines
    V. N. Kozhevnikov
    D. N. Kozhevnikov
    O. V. Shabunina
    N. N. Kataeva
    S. A. Yushchuk
    V. L. Rusinov
    O. N. Chupakhin
    Russian Chemical Bulletin, 2005, 54 : 2187 - 2196
12345