Methylglyoxal Impairs GLUT4 Trafficking and Leads to Increased Glucose Uptake in L6 Myoblasts

被引:0
|
作者
Engelbrecht, B. [1 ]
Mattern, Y. [1 ]
Scheibler, S. [1 ]
Tschoepe, D. [1 ]
Gawlowski, T. [1 ]
Stratmann, B. [1 ]
机构
[1] Ruhr Univ Bochum, Heart & Diabet Ctr NRW, Ctr Diabet, D-32545 Bad Oeynhausen, Germany
关键词
GLYCATION END-PRODUCTS; PROTEIN-KINASE-B; OXIDATIVE STRESS; INSULIN-RESISTANCE; GLYOXALASE SYSTEM; DIABETES-MELLITUS; ACTIVATION; GLUCOSE-TRANSPORTER-4; TRANSLOCATION; GLYCOSYLATION;
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:77 / 84
页数:8
相关论文
共 50 条
  • [31] DIFFERENTIAL EXPRESSION OF THE GLUT1 AND GLUT4 GLUCOSE TRANSPORTERS DURING DIFFERENTIATION OF L6 MUSCLE-CELLS
    MITSUMOTO, Y
    BURDETT, E
    GRANT, A
    KLIP, A
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1991, 175 (02) : 652 - 659
  • [32] THE COOH-TERMINAL CYTOPLASMIC DOMAIN OF THE GLUT4 GLUCOSE TRANSPORTER DETERMINES ITS INTRACELLULAR TARGETING TO AN INSULIN-SENSITIVE COMPARTMENT IN L6 MYOBLASTS
    HANEY, PM
    MUECKLER, MM
    CLINICAL RESEARCH, 1993, 41 (02): : A274 - A274
  • [33] Acacetin enhances glucose uptake through insulin-independent GLUT4 translocation in L6 myotubes (vol 68, 153178, 2020)
    Kwon, Eun-Bin
    Kang, Myung-Ji
    Ryu, Hyung Won
    Lee, Seoghyun
    Lee, Jae-Won
    Lee, Mi Kyeong
    Lee, Hyun-Sun
    Lee, Su Ui
    Oh, Sei-Ryang
    Kim, Mun-Ock
    PHYTOMEDICINE, 2021, 80
  • [34] Labeling and imaging of GLUT4 in live L6 cells with quantum dots
    Wang, Xiaoxuan
    Qu, Feng
    Chen, Zubin
    Liang, Tao
    Ou, Anlian
    BIOCHEMISTRY AND CELL BIOLOGY, 2009, 87 (04) : 687 - 694
  • [35] N4BP2L1 interacts with dynactin and contributes to GLUT4 trafficking and glucose uptake in adipocytes
    Watanabe, Kazuhisa
    Matsumoto, Ayumi
    Tsuda, Hidetoshi
    Iwamoto, Sadahiko
    JOURNAL OF DIABETES INVESTIGATION, 2021, 12 (11) : 1958 - 1966
  • [36] Atorvastatin induces glucose uptake via GLUT-4 in L6 skeletal muscle cells
    Gruber, HJ
    Mayer, CM
    Landl, EM
    Panzenböck, U
    Sattler, W
    Scharnagl, H
    März, W
    ATHEROSCLEROSIS SUPPLEMENTS, 2005, 6 (01) : 108 - 108
  • [37] Vamp-2, not cellubrevin, plays a critical role in insulin-stimulated GLUT4 translocation in l6 myoblasts.
    Randhawa, VK
    Bilan, PJ
    Daneman, N
    Daneman, N
    Bilan, PJ
    Bilan, PJ
    Peng, XR
    Coppola, T
    Regazzi, R
    Trimble, WS
    Klip, A
    MOLECULAR BIOLOGY OF THE CELL, 1999, 10 : 85A - 85A
  • [38] Cellular Regulation of Glucose Uptake by Glucose Transporter GLUT4
    Govers, Roland
    ADVANCES IN CLINICAL CHEMISTRY, VOL 66, 2014, 66 : 173 - 240
  • [39] In L6 skeletal muscle cells, antisense inhibition of PED expression increases insulin-stimulated glucose uptake and GLUT4 membrane recruitment
    Beguinot, F
    Vigliotta, G
    Caruso, M
    Cafieri, A
    Trencia, A
    Andalo, P
    Condorelli, G
    DIABETES, 1999, 48 : A25 - A25
  • [40] Lack of CD2AP disrupts Glut4 trafficking and attenuates glucose uptake
    Tolvanen, T. A.
    Dash, S. N.
    Polianskyte, Z.
    Dumont, V.
    Lehtonen, S.
    DIABETOLOGIA, 2015, 58 : S295 - S295