STUDY OF EFFICACY OF PLATELET RICH PLASMA DRESSING IN MANAGEMENT OF CHRONIC NON-HEALING LEG ULCERS

BACKGROUND Diabetic foot ulcers continue to be a significant global issue despite the advances made in the management of diabetes. It causes major foot complications if they are not addressed properly. It needs multidisciplinary approach for its care. While several advancements have taken place in wound care management, platelet rich plasma and stem cell therapy promise to offer a new hope in its management, aiding in cellular and tissue regeneration. The purpose of the present study was to compare Platelet-Rich Plasma versus conventional dressing in the management of diabetic foot ulcers. METHODS Patients presented with chronic non healing ulcers were recruited in this study. This was a prospective study conducted at Krishna Hospital & Medical Research Centre, Karad. A total of 50 patients was assigned. They were grouped through computerized randomization into two groups. Control group patients were treated with conventional dressing and study group patients were treated with platelet rich plasma (PRP) dressing and observed for reduction in the wound size in a span of 21 days. RESULTS The study group patients showed higher reduction in wound size of about 43.40 % as against 14.03 % in the control group with p value < 0.001. CONCLUSIONS Platelet rich plasma dressing significantly increases incidence of wound healing in chronic lower limb ulcers.